VeriMommelia azadirachta (neem) leaf est-il sûr pendant la grossesse ?
Animal studies report reproductive/antifertility effects from neem/Melia extracts (seed extracts inhibited folliculogenesis in rats; some neem leaf extracts produced altered fetal ossification at high oral doses), so this meets 'suspected' (h=2). Mechanistic evidence shows demonstrated effects on ovarian folliculogenesis/fertility in animals (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure for typical adult topical use is low (e=1). Sources: animal reproductive studies and a maternal–fetal rat study. (PubMed: Roop et al. 2005; Ramalho et al. 2023; see sources list).
Alternatives sûres à melia azadirachta (neem) leaf pendant la grossesse | VeriMom
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Frequently asked questions
- melia azadirachta (neem) leaf est-il sûr pendant la grossesse ?
- Animal studies report reproductive/antifertility effects from neem/Melia extracts (seed extracts inhibited folliculogenesis in rats; some neem leaf extracts produced altered fetal ossification at high oral doses), so this meets 'suspected' (h=2). Mechanistic evidence shows demonstrated effects on ovarian folliculogenesis/fertility in animals (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure for typical adult topical use is low (e=1). Sources: animal reproductive studies and a maternal–fetal rat study. (PubMed: Roop et al. 2005; Ramalho et al. 2023; see sources list).
- melia azadirachta (neem) leaf est-il sûr pendant l'allaitement ?
- Same hazard and mechanism considerations as pregnancy because animal data show effects on reproduction and development; for topical cosmetics maternal systemic exposure is likely low but measurable, so potential for excretion into milk is possible though not established (thus e=1).
- melia azadirachta (neem) leaf est-il sûr pour la peau de bébé ?
- No infant-specific toxicology demonstrating developmental/reproductive effects from topical exposure; therefore hazard is lowered to a precautionary class-based/structural concern (h=1) because botanical extracts can contain bioactive constituents. Mechanistic pregnancy-level endocrine evidence is from systemic/oral animal studies, not infant-skin specific (m=0). Exposure is increased by one category for baby skin (immature barrier/higher SA:BW) from the adult topical level (adult e=1 → baby e=2).
- Comment VeriMom évalue-t-il melia azadirachta (neem) leaf ?
- VeriMom évalue melia azadirachta (neem) leaf à 40/100 (risque moyen) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à melia azadirachta (neem) leaf pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à melia azadirachta (neem) leaf basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.