melia azadirachta (neem) extract est-il sûr pendant la grossesse ?
Animal studies reported reproductive effects after systemic (oral) dosing of neem/Melia extracts (e.g., inhibition of folliculogenesis in rats; maternal‑fetal study showed a change in sternal ossification at high oral dose), and this constitutes animal reproductive evidence warranting a 'suspected' reproductive hazard. There is no EU Annex II/III listing or harmonised CLP classification for the CAS 90063-92-6 extract, and no SCCS or CIR cosmetic opinion that overrides the animal data. (See PubMed studies and safety/review sources below).
Alternatives sûres à melia azadirachta (neem) extract pendant la grossesse | VeriMom
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Frequently asked questions
- melia azadirachta (neem) extract est-il sûr pendant la grossesse ?
- Animal studies reported reproductive effects after systemic (oral) dosing of neem/Melia extracts (e.g., inhibition of folliculogenesis in rats; maternal‑fetal study showed a change in sternal ossification at high oral dose), and this constitutes animal reproductive evidence warranting a 'suspected' reproductive hazard. There is no EU Annex II/III listing or harmonised CLP classification for the CAS 90063-92-6 extract, and no SCCS or CIR cosmetic opinion that overrides the animal data. (See PubMed studies and safety/review sources below).
- melia azadirachta (neem) extract est-il sûr pendant l'allaitement ?
- Same rationale as pregnancy: systemic animal reproductive/developmental findings after oral dosing indicate a suspected hazard if there were systemic exposure. For topical cosmetic use breastfeeding exposure is expected to be negligible, but systemic maternal exposure (oral or high systemic) could be relevant. No authoritative regulatory breastfeeding-specific restrictions found.
- melia azadirachta (neem) extract est-il sûr pour la peau de bébé ?
- Hazard (h) remains at 2 because the scoring is driven by animal reproductive/developmental evidence. Mechanistic evidence (enzyme/biological activity of neem constituents and reported effects on follicles/ossification in animal studies) supports m=2. For exposure (e) increase by +1 for infants (immature skin barrier and higher SA:BW) so e=1 for baby (0–3 yr) topical scenarios; adult topical absorption for cosmetic use is judged low/negligible.
- Comment VeriMom évalue-t-il melia azadirachta (neem) extract ?
- VeriMom évalue melia azadirachta (neem) extract à 47/100 (risque moyen) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à melia azadirachta (neem) extract pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à melia azadirachta (neem) extract basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.