VeriMomhydrastis canadensis extract est-il sûr pendant la grossesse ?
Animal developmental/reproductive studies of berberine (a major alkaloid in Hydrastis canadensis) show developmental/embryotoxic effects and maternal toxicity in rodent studies; berberine can cross the placenta (animal and in vitro data) and authoritative agencies advise avoiding goldenseal/berberine in pregnancy. No EU Annex II/III ban or harmonised CLP (H360/H361) was identified for the extract itself. Sources: PubMed developmental studies; ANSES/ESCOP guidance; PubMed review. (See sources.)
Alternatives sûres à hydrastis canadensis extract pendant la grossesse | VeriMom
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Frequently asked questions
- hydrastis canadensis extract est-il sûr pendant la grossesse ?
- Animal developmental/reproductive studies of berberine (a major alkaloid in Hydrastis canadensis) show developmental/embryotoxic effects and maternal toxicity in rodent studies; berberine can cross the placenta (animal and in vitro data) and authoritative agencies advise avoiding goldenseal/berberine in pregnancy. No EU Annex II/III ban or harmonised CLP (H360/H361) was identified for the extract itself. Sources: PubMed developmental studies; ANSES/ESCOP guidance; PubMed review. (See sources.)
- hydrastis canadensis extract est-il sûr pendant l'allaitement ?
- Berberine is reported to be excreted into breastmilk and agencies/authors advise against goldenseal/berberine during lactation because of potential infant exposure and risks (including bilirubin displacement/jaundice concerns). Evidence supports measurable transfer (mechanism demonstrated) although human quantitative milk data are limited.
- hydrastis canadensis extract est-il sûr pour la peau de bébé ?
- No infant-specific reproductive toxicity data for topical cosmetic use were identified. The constituent berberine has demonstrated developmental hazards in animals, so a conservative hazard flag at class/constituent level is appropriate (h=1 for baby skin absent infant-specific data). Topical exposure on infant skin yields increased exposure score (+1) because infant skin barrier is immature and any measurable dermal absorption for adults becomes higher for infants; dermal absorption for plant alkaloids is low-to-moderate but not zero.
- Comment VeriMom évalue-t-il hydrastis canadensis extract ?
- VeriMom évalue hydrastis canadensis extract à 40/100 (risque moyen) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à hydrastis canadensis extract pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à hydrastis canadensis extract basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.