VeriMomglycyrrhiza uralensis root extract est-il sûr pendant la grossesse ?
No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR conclusion that this extract is a reproductive teratogen; therefore hazard score remains 0 per rules. However, multiple peer-reviewed reports show constituent-specific endocrine activity in vitro (e.g., liquiritigenin is an ER agonist; glycyrrhizin/glycyrrhetinic acid have biological activity), so a demonstrated mechanistic effect is present (m=2). For topical use, systemic exposure is low but measurable depending on formulation, so exposure scored as 1. Sources: ECHA (no harmonised classification), PubMed (in vitro endocrine activity of licorice constituents), PubChem (constituent data), CosIng/EWG summaries.
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Frequently asked questions
- glycyrrhiza uralensis root extract est-il sûr pendant la grossesse ?
- No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR conclusion that this extract is a reproductive teratogen; therefore hazard score remains 0 per rules. However, multiple peer-reviewed reports show constituent-specific endocrine activity in vitro (e.g., liquiritigenin is an ER agonist; glycyrrhizin/glycyrrhetinic acid have biological activity), so a demonstrated mechanistic effect is present (m=2). For topical use, systemic exposure is low but measurable depending on formulation, so exposure scored as 1. Sources: ECHA (no harmonised classification), PubMed (in vitro endocrine activity of licorice constituents), PubChem (constituent data), CosIng/EWG summaries.
- glycyrrhiza uralensis root extract est-il sûr pendant l'allaitement ?
- No human/animal data establishing reproductive or developmental toxicity via dermal cosmetic use or lactation and no harmonised classification; hazard remains 0. Mechanistic in vitro endocrine activity of constituents supports m=2. Dermal absorption from cosmetics is low but measurable; breastmilk transfer after topical cosmetic use is unlikely but not well studied, so exposure scored 1. Sources: PubMed (constituent endocrine activity), ECHA (no CLP reprotox classification), PubChem, EWG.
- glycyrrhiza uralensis root extract est-il sûr pour la peau de bébé ?
- No infant-specific evidence of reproductive/developmental toxicity from cosmetic topical use and no harmonised reprotoxic classification; hazard remains 0. Mechanistic evidence (in vitro estrogenic activity of constituents) justifies m=2. Exposure is increased for babies vs adults due to immature barrier and higher surface-area-to-weight; adult exposure scored 1 -> baby exposure increased to 2. Sources: PubMed (mechanistic studies on liquiritigenin/glycyrrhizin), CosIng/PubChem summaries, EWG.
- Comment VeriMom évalue-t-il glycyrrhiza uralensis root extract ?
- VeriMom évalue glycyrrhiza uralensis root extract à 80/100 (risque faible) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à glycyrrhiza uralensis root extract pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à glycyrrhiza uralensis root extract basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.