VeriMomcis-3,5,5-trimethylcyclohexanol est-il sûr pendant la grossesse ?
No harmonised CLP reproductive classification or SCCS/CIR safety assessment was found for cis-3,3,5‑trimethylcyclohexanol (CAS 933‑48‑2). PubMed/PMC pharmacokinetic/metabolism studies show the substance is absorbed/metabolised (glucuronidation in rat hepatocytes), indicating low but measurable systemic exposure after absorption, so exposure (e) is scored 1. Sources searched show hepatic/metabolism studies but no reproductive or teratogenic data. (See PubMed/PMC and ECHA registration data.)
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Frequently asked questions
- cis-3,5,5-trimethylcyclohexanol est-il sûr pendant la grossesse ?
- No harmonised CLP reproductive classification or SCCS/CIR safety assessment was found for cis-3,3,5‑trimethylcyclohexanol (CAS 933‑48‑2). PubMed/PMC pharmacokinetic/metabolism studies show the substance is absorbed/metabolised (glucuronidation in rat hepatocytes), indicating low but measurable systemic exposure after absorption, so exposure (e) is scored 1. Sources searched show hepatic/metabolism studies but no reproductive or teratogenic data. (See PubMed/PMC and ECHA registration data.)
- cis-3,5,5-trimethylcyclohexanol est-il sûr pendant l'allaitement ?
- No evidence of reproductive or lactation-specific toxicity or human teratogenicity was identified in the literature or in ECHA registration records. Metabolism data (rat hepatocytes; glucuronide formation) indicate the compound can be systemically available after absorption, so breastfeeding exposure is scored as low but measurable (e=1). No studies reporting transfer into milk or effects on nursing infants were found.
- cis-3,5,5-trimethylcyclohexanol est-il sûr pour la peau de bébé ?
- No infant-specific toxicity or developmental effects were identified. Because (a) the compound shows measurable uptake/metabolism in in vitro/in vivo models (rats/hepatocytes) and (b) infant skin has higher absorption per body weight, I increased exposure for baby skin by +1 (adult e=1 → baby e=2). There is no evidence to increase hazard (h) or mechanism (m) for infants in available studies.
- Comment VeriMom évalue-t-il cis-3,5,5-trimethylcyclohexanol ?
- VeriMom évalue cis-3,5,5-trimethylcyclohexanol à 93/100 (pas de risques connus) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à cis-3,5,5-trimethylcyclohexanol pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à cis-3,5,5-trimethylcyclohexanol basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.