butyrolactone est-il sûr pendant la grossesse ?
No harmonised reproductive classification (no H360/H361 on ECHA substance listing) and no CIR or SCCS reproductive safety opinion was found for butyrolactone/γ‑butyrolactone; available regulatory and safety documents describe acute toxicity and misuse risk on ingestion but do not identify reproductive teratogenicity from dermal/cosmetic use. Topical exposure could give low but measurable systemic exposure because GBL is a small, water‑miscible molecule that is absorbed and readily metabolised to GHB after systemic uptake, so exposure score is 1 for pregnancy (adult topical). Sources: ECHA substance page; SDSs/regulatory summaries; CDC/FDA reviews of ingestion risks.
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Frequently asked questions
- butyrolactone est-il sûr pendant la grossesse ?
- No harmonised reproductive classification (no H360/H361 on ECHA substance listing) and no CIR or SCCS reproductive safety opinion was found for butyrolactone/γ‑butyrolactone; available regulatory and safety documents describe acute toxicity and misuse risk on ingestion but do not identify reproductive teratogenicity from dermal/cosmetic use. Topical exposure could give low but measurable systemic exposure because GBL is a small, water‑miscible molecule that is absorbed and readily metabolised to GHB after systemic uptake, so exposure score is 1 for pregnancy (adult topical). Sources: ECHA substance page; SDSs/regulatory summaries; CDC/FDA reviews of ingestion risks.
- butyrolactone est-il sûr pendant l'allaitement ?
- No authoritative reproductive/breastfeeding safety assessment (CIR/SCCS/harmonised CLP) flagging developmental or lactation hazards. Systemic exposure from topical use is expected to be low but measurable in adults; because GBL converts to GHB systemically, breastmilk transfer would only be a concern if significant maternal systemic levels occur (not typical from normal cosmetic topical use). Thus hazard/mechanism remain 0; exposure scored 1 (low but measurable). Sources: ECHA substance information; LactMed/GHB references and FDA/CDC warnings about systemic effects from ingestion rather than topical use.
- butyrolactone est-il sûr pour la peau de bébé ?
- No infant‑specific reproductive/developmental toxicity evidence from authoritative cosmetic safety bodies. Per scoring rules, because adult topical exposure is scored as 1 (measurable), infant skin exposure is increased by +1 (immature barrier and higher SA:BW) to give e=2 (moderate). There is no infant‑specific data showing placental or dermal developmental hazards; the main concern in literature is systemic GHB effects after ingestion/large exposures, not routine topical cosmetic use. Sources: ECHA substance page; EPA/EPA inert reassessment and SDSs describing routes of concern (ingestion/systemic), and EWG ingredient entry.
- Comment VeriMom évalue-t-il butyrolactone ?
- VeriMom évalue butyrolactone à 93/100 (pas de risques connus) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à butyrolactone pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à butyrolactone basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.