VeriMomammonium glycyrrhizate est-il sûr pendant la grossesse ?
CIR’s final safety assessment includes ammonium glycyrrhizate and judges cosmetic use acceptable with typical use conditions, but independent human/epidemiological and toxicology assessments link glycyrrhizic/glycyrrhetinic acids (parent compounds) with pregnancy outcomes after oral exposure via inhibition of placental 11β‑HSD2 and associated fetal effects; therefore reproductive concern is suspected (h=2) with a demonstrated mechanism (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure score is 1. (Sources: CIR final report; VKM risk assessment; PBPK and human studies summarized in LactMed and literature).
Alternatives sûres à ammonium glycyrrhizate pendant la grossesse | VeriMom
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Frequently asked questions
- ammonium glycyrrhizate est-il sûr pendant la grossesse ?
- CIR’s final safety assessment includes ammonium glycyrrhizate and judges cosmetic use acceptable with typical use conditions, but independent human/epidemiological and toxicology assessments link glycyrrhizic/glycyrrhetinic acids (parent compounds) with pregnancy outcomes after oral exposure via inhibition of placental 11β‑HSD2 and associated fetal effects; therefore reproductive concern is suspected (h=2) with a demonstrated mechanism (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure score is 1. (Sources: CIR final report; VKM risk assessment; PBPK and human studies summarized in LactMed and literature).
- ammonium glycyrrhizate est-il sûr pendant l'allaitement ?
- Glycyrrhizic acid (parent) has been detected in breastmilk after maternal oral intake and systemic effects are reported with ingestion; mechanism (11β‑HSD2 inhibition and systemic glycyrrhetinic metabolites) is demonstrated. For topical cosmetic use transfer to milk from topical use is unlikely but possible at low measurable levels, so exposure =1 and hazard =2 pending significant systemic exposure. (Sources: LactMed/NCBI; CIR; VKM).
- ammonium glycyrrhizate est-il sûr pour la peau de bébé ?
- No infant‑specific topical hazard data found; hazard and mechanism remain linked to the parent glycyrrhizic/glycyrrhetinic acids (h=2, m=2). Because infant skin has higher per‑kg absorption, raise exposure by +1 compared with adults (adult e=1 → infant e=2) when the ingredient shows measurable absorption. No evidence supports increasing hazard or mechanism scores for infants in the absence of infant‑specific toxicology. (Sources: CIR; VKM; LactMed).
- Comment VeriMom évalue-t-il ammonium glycyrrhizate ?
- VeriMom évalue ammonium glycyrrhizate à 40/100 (risque moyen) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à ammonium glycyrrhizate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à ammonium glycyrrhizate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.