Dois-je éviter trimethylbenzoyl diphenylphosphine oxide pendant la grossesse ? | VeriMom
Diphenyl(2,4,6‑trimethylbenzoyl)phosphine oxide (TPO) has a harmonised CLP classification Repr. 1B, H360Fd (may damage fertility; suspected of damaging the unborn child), which by calibration dictates h=3. Animal/reproductive data and regulatory assessments document reproductive/developmental effects (supporting a demonstrated mechanism), while dermal exposure from cosmetic nail use is low but measurable. ([echa.europa.eu](https://echa.europa.eu/web/guest/brief-profile/-/briefprofile/100.071.211?utm_source=openai))
ECHA regulatory hazard statements
- •H360FD
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- trimethylbenzoyl diphenylphosphine oxide est-il sûr pendant la grossesse ?
- Diphenyl(2,4,6‑trimethylbenzoyl)phosphine oxide (TPO) has a harmonised CLP classification Repr. 1B, H360Fd (may damage fertility; suspected of damaging the unborn child), which by calibration dictates h=3. Animal/reproductive data and regulatory assessments document reproductive/developmental effects (supporting a demonstrated mechanism), while dermal exposure from cosmetic nail use is low but measurable. ([echa.europa.eu](https://echa.europa.eu/web/guest/brief-profile/-/briefprofile/100.071.211?utm_source=openai))
- trimethylbenzoyl diphenylphosphine oxide est-il sûr pendant l'allaitement ?
- Because the substance carries a harmonised Repr. 1B (H360Fd) classification, it is scored h=3 for breastfeeding context as well (harmonised CMR classifications indicate confirmed concern independent of route). Mechanistic support comes from animal reproductive/developmental findings noted in dossiers and assessments. Typical topical use (nail products) gives low but measurable dermal exposure; specific transfer into breast milk is not documented in public dossiers. ([echa.europa.eu](https://echa.europa.eu/web/guest/brief-profile/-/briefprofile/100.071.211?utm_source=openai))
- trimethylbenzoyl diphenylphosphine oxide est-il sûr pour la peau de bébé ?
- Harmonised Repr.1B (H360Fd) sets h=3 for infants when considering potential harm; mechanism supported by animal reproductive/toxicology findings. Dermal exposure for baby skin is increased relative to adults because infant skin has higher permeability and surface‑area‑to‑weight; therefore exposure score is adult+1 (1→2) given measurable dermal absorption from cosmetic use and absence of evidence showing zero absorption. No infant‑specific dermal toxicokinetic studies were found. ([echa.europa.eu](https://echa.europa.eu/web/guest/brief-profile/-/briefprofile/100.071.211?utm_source=openai))
- Comment VeriMom évalue-t-il trimethylbenzoyl diphenylphosphine oxide ?
- VeriMom évalue trimethylbenzoyl diphenylphosphine oxide à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à trimethylbenzoyl diphenylphosphine oxide pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à trimethylbenzoyl diphenylphosphine oxide basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.