VeriMomDois-je éviter sodium picramate pendant la grossesse ? | VeriMom
Harmonised classification for sodium picramate/picramic acid includes Repr. 1B H360F (“May damage fertility”) in ECHA/CLP-related registrations and dossiers; per your calibration H360→h=3. SCCS has evaluated picramic acid/sodium picramate for hair-dye use and set restricted maximum on-head concentration (0.6% in non-oxidative hair dyes), indicating systemic/repro concern driving the restriction. Evidence for a specific molecular reproductive mechanism is limited in available reviews (so m=1). Topical hair-dye use can lead to low but measurable systemic exposure in adults (SCCS restriction), so e=1.
ECHA regulatory hazard statements
- •H360F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- sodium picramate est-il sûr pendant la grossesse ?
- Harmonised classification for sodium picramate/picramic acid includes Repr. 1B H360F (“May damage fertility”) in ECHA/CLP-related registrations and dossiers; per your calibration H360→h=3. SCCS has evaluated picramic acid/sodium picramate for hair-dye use and set restricted maximum on-head concentration (0.6% in non-oxidative hair dyes), indicating systemic/repro concern driving the restriction. Evidence for a specific molecular reproductive mechanism is limited in available reviews (so m=1). Topical hair-dye use can lead to low but measurable systemic exposure in adults (SCCS restriction), so e=1.
- sodium picramate est-il sûr pendant l'allaitement ?
- Harmonised classification (H360F) applies regardless of exposure route; therefore h=3. No robust data were located demonstrating mechanism or mammary‑transfer studies (m=1). Given likely limited systemic absorption from typical topical hair‑dye use but non-zero (SCCS restriction), maternal systemic exposure — and therefore potential, low breast‑milk exposure — is possible (e=1).
- sodium picramate est-il sûr pour la peau de bébé ?
- Hazard (H360F) remains the relevant intrinsic property so h=3 (do not up‑rank hazard without infant‑specific evidence). Mechanistic evidence for a reproductive pathway is limited (m=1). Because infant skin has higher absorption per weight and immature barrier, and adult topical use shows measurable absorption, increase exposure by +1 for 0–3 yr (adult e=1 → baby e=2). No infant‑specific toxicokinetic or dermal absorption studies were found.
- Comment VeriMom évalue-t-il sodium picramate ?
- VeriMom évalue sodium picramate à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à sodium picramate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à sodium picramate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.