VeriMomDois-je éviter silver pendant la grossesse ? | VeriMom
Silver (CAS 7440-22-4) has a harmonised CLP classification in Annex VI as Repr. Cat. 2 H361f (suspected of damaging fertility) for multiple physical forms, so reproductive hazard is indicated (h=2). Animal and mechanistic data (ionic silver/Ag+ and nanosilver biodistribution; PBPK and developmental/reproductive studies with silver salts and nanoparticles) show demonstrated systemic distribution and effects in rodents, supporting a mechanistic concern (m=2). For routine topical cosmetic use, skin absorption of particle forms is low (SCCS notes micron-sized particulate silver does not penetrate intact skin), so exposure from typical topical use is low but measurable (elevated for soluble/ionic forms and some nanoparticles) (e=1).
ECHA regulatory hazard statements
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- silver est-il sûr pendant la grossesse ?
- Silver (CAS 7440-22-4) has a harmonised CLP classification in Annex VI as Repr. Cat. 2 H361f (suspected of damaging fertility) for multiple physical forms, so reproductive hazard is indicated (h=2). Animal and mechanistic data (ionic silver/Ag+ and nanosilver biodistribution; PBPK and developmental/reproductive studies with silver salts and nanoparticles) show demonstrated systemic distribution and effects in rodents, supporting a mechanistic concern (m=2). For routine topical cosmetic use, skin absorption of particle forms is low (SCCS notes micron-sized particulate silver does not penetrate intact skin), so exposure from typical topical use is low but measurable (elevated for soluble/ionic forms and some nanoparticles) (e=1).
- silver est-il sûr pendant l'allaitement ?
- Harmonised classification (H361f) and animal data justify a suspected reproductive hazard also relevant to lactation exposures (h=2). Mechanistic and PK literature document systemic absorption/distribution of ionic silver and some nanoparticle transformation with potential for transfer to tissues (m=2). Available data on topical cosmetics indicate low dermal absorption for particulate silver, so milk exposure from typical topical use is expected to be low but not zero (e=1).
- silver est-il sûr pour la peau de bébé ?
- Hazard scoring remains based on the harmonised H361f classification and supporting animal/mechanistic evidence (h=2, m=2). Because infant skin has a higher surface-area-to-weight ratio and an immature barrier, exposure from topical application is increased by +1 compared with adults when measurable absorption exists; therefore exposure for baby skin is scored e=2. There is limited evidence for direct infant-specific developmental effects from topical cosmetic exposures, but systemic ionic silver and some nanosilver forms have produced reproductive/developmental effects in animal studies.
- Comment VeriMom évalue-t-il silver ?
- VeriMom évalue silver à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à silver pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à silver basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.