VeriMomDois-je éviter sassafras officinale bark extract pendant la grossesse ? | VeriMom
Sassafras bark/root extracts can contain the alkenylbenzene safrole, which is harmonised/classified in the EU as a carcinogen (CLP Category 1B/H350/H351) and is prohibited in cosmetics; carcinogenic/mutagenic hazards are treated as high reproductive concern. Safrole’s metabolic activation leads to DNA adduct formation (demonstrated mechanism). Exposure from topical cosmetic use is low–but measurable unless the extract is guaranteed safrole-free. (ECHA substance data; NTP/Report on Carcinogens; PubMed reviews of alkenylbenzenes).
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FAQ
- sassafras officinale bark extract est-il sûr pendant la grossesse ?
- Sassafras bark/root extracts can contain the alkenylbenzene safrole, which is harmonised/classified in the EU as a carcinogen (CLP Category 1B/H350/H351) and is prohibited in cosmetics; carcinogenic/mutagenic hazards are treated as high reproductive concern. Safrole’s metabolic activation leads to DNA adduct formation (demonstrated mechanism). Exposure from topical cosmetic use is low–but measurable unless the extract is guaranteed safrole-free. (ECHA substance data; NTP/Report on Carcinogens; PubMed reviews of alkenylbenzenes).
- sassafras officinale bark extract est-il sûr pendant l'allaitement ?
- Same basis as pregnancy: presence of safrole (harmonised EU classification as a CMR) makes the ingredient high hazard for lactation context. Topical exposures are low–but measurable; transfer into milk is not well characterised for cosmetic topical use, but CMR classification and genotoxic mechanism justify a high hazard rating. (ECHA; NTP; SCF/PubMed reviews).
- sassafras officinale bark extract est-il sûr pour la peau de bébé ?
- Hazard and mechanism mirror adult/pregnancy because safrole is a harmonised CMR 1B. Exposure score is increased for infants (+1) because infant skin has higher surface-area-to-weight and less mature barrier, so a measurable topical exposure becomes a moderate exposure for 0–3 yr. Where the extract is confirmed safrole-free, these scores would change. (ECHA; NTP; PubMed reviews).
- Comment VeriMom évalue-t-il sassafras officinale bark extract ?
- VeriMom évalue sassafras officinale bark extract à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à sassafras officinale bark extract pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à sassafras officinale bark extract basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.