VeriMomDois-je éviter retinyl retinoate pendant la grossesse ? | VeriMom
No harmonised ECHA H360 classification or specific reproductive/teratology studies were located for retinyl retinoate itself, so a confirmed H360-level hazard cannot be assigned; however it is a retinoid ester that can produce retinoid activity and retinoic-acid-mediated developmental effects are well‑characterised, so a class-based theoretical reproductive concern is justified (h=1). The mechanism is well‑characterised as retinoic acid receptor agonism and metabolic conversion to active retinoid species in skin (m=3). Topical absorption is low but measurable for retinyl esters per SCCS (exposure order: retinyl esters << retinol < retinal < retinoic acid), so adult topical exposure is scored low but measurable (e=1).
ECHA regulatory hazard statements
- •H360
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- retinyl retinoate est-il sûr pendant la grossesse ?
- No harmonised ECHA H360 classification or specific reproductive/teratology studies were located for retinyl retinoate itself, so a confirmed H360-level hazard cannot be assigned; however it is a retinoid ester that can produce retinoid activity and retinoic-acid-mediated developmental effects are well‑characterised, so a class-based theoretical reproductive concern is justified (h=1). The mechanism is well‑characterised as retinoic acid receptor agonism and metabolic conversion to active retinoid species in skin (m=3). Topical absorption is low but measurable for retinyl esters per SCCS (exposure order: retinyl esters << retinol < retinal < retinoic acid), so adult topical exposure is scored low but measurable (e=1).
- retinyl retinoate est-il sûr pendant l'allaitement ?
- No direct data on transfer of retinyl retinoate into human milk were found. By analogy to other topical retinoid esters and because retinoids have a known receptor‑mediated mechanism, a theoretical class-based concern for nursing infants applies (h=1) and the mechanism remains retinoid receptor activity (m=3). Systemic exposure from typical topical cosmetic use is expected to be low but measurable, so exposure via maternal use during breastfeeding is scored low (e=1).
- retinyl retinoate est-il sûr pour la peau de bébé ?
- No infant-specific toxicology studies for retinyl retinoate were found. Hazard remains a class-based theoretical retinoid concern (h=1) with the same retinoid receptor mechanism (m=3). Because infant skin (0–3 yr) has higher surface-area-to-weight and an immature barrier, exposure score is increased by +1 from adult topical use (adult e=1 → baby e=2) when measurable dermal absorption exists. Note: SCCS has evaluated retinol and common retinyl esters and recommends concentration limits/warnings; retinoic acid itself is banned in cosmetics (SCCS).
- Comment VeriMom évalue-t-il retinyl retinoate ?
- VeriMom évalue retinyl retinoate à 13/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à retinyl retinoate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à retinyl retinoate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.