VeriMomDois-je éviter retinyl propionate pendant la grossesse ? | VeriMom
Animal and toxicology literature show that preformed vitamin A and retinoids (including retinyl esters) cause dose‑dependent embryofetal malformations in multiple species; expert panels (CIR, SCCS) have reviewed retinol/retinyl esters for cosmetics. ECHA/industry dossiers and supplier SDSs list reproductive hazard statements (H360/H361) as self‑classified for retinyl propionate, and animal data (e.g., rodent/macaque studies of retinyl esters/retinoic acid) demonstrate teratogenicity. Topical cosmetic use gives low but measurable dermal absorption, so systemic exposure is generally low but not zero. Sources: CIR (retinol/retinyl esters safety assessment), SCCS opinions on vitamin A, ECHA registration / supplier SDSs, peer‑reviewed animal teratogenicity studies.
ECHA regulatory hazard statements
- •H360
- •H361d
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- retinyl propionate est-il sûr pendant la grossesse ?
- Animal and toxicology literature show that preformed vitamin A and retinoids (including retinyl esters) cause dose‑dependent embryofetal malformations in multiple species; expert panels (CIR, SCCS) have reviewed retinol/retinyl esters for cosmetics. ECHA/industry dossiers and supplier SDSs list reproductive hazard statements (H360/H361) as self‑classified for retinyl propionate, and animal data (e.g., rodent/macaque studies of retinyl esters/retinoic acid) demonstrate teratogenicity. Topical cosmetic use gives low but measurable dermal absorption, so systemic exposure is generally low but not zero. Sources: CIR (retinol/retinyl esters safety assessment), SCCS opinions on vitamin A, ECHA registration / supplier SDSs, peer‑reviewed animal teratogenicity studies.
- retinyl propionate est-il sûr pendant l'allaitement ?
- Mechanism (retinoid activity) is the same and systemic exposure from topical use is low but measurable; transferred levels in breastmilk after topical cosmetic use are not well quantified. Given the known developmental effects of systemic retinoids, breastfeeding risk is considered linked to maternal systemic exposure (which for cosmetic topical use is generally low). Relevant sources: CIR, SCCS, ECHA dossiers/SDS, animal/developmental literature.
- retinyl propionate est-il sûr pour la peau de bébé ?
- No infant‑specific developmental hazard data were located; however, retinyl propionate is a retinol ester metabolised to active retinoids (mechanistic concern). Infant skin has higher absorption (immature barrier, higher surface‑area‑to‑weight), so exposure score is increased by +1. There is a lack of infant dermal PK data for retinyl propionate specifically. Sources: CIR and SCCS reviews of retinol/retinyl esters; general toxicology literature on retinoid embryopathy; ECHA registration/SDS noting reproductive hazard classifications.
- Comment VeriMom évalue-t-il retinyl propionate ?
- VeriMom évalue retinyl propionate à 13/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à retinyl propionate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à retinyl propionate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.