VeriMomDois-je éviter retinyl palmitate pendant la grossesse ? | VeriMom
Retinyl palmitate is associated with developmental/teratogenic effects in animal oral studies (rats/rabbits) and is a source of retinoic acid activity; this supports a 'suspected' reproductive hazard rather than a harmonised Category 1 human teratogen classification. The mechanistic basis is well characterized (retinoid → retinoic acid, RAR agonism). For topical cosmetic use systemic exposure is low but measurable; regulatory actions in the EU are moving to limit vitamin A equivalents in cosmetics and require labelling, reflecting concern over systemic exposure. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8884871/))
ECHA regulatory hazard statements
- •H360
- •H361
- •H361d
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- retinyl palmitate est-il sûr pendant la grossesse ?
- Retinyl palmitate is associated with developmental/teratogenic effects in animal oral studies (rats/rabbits) and is a source of retinoic acid activity; this supports a 'suspected' reproductive hazard rather than a harmonised Category 1 human teratogen classification. The mechanistic basis is well characterized (retinoid → retinoic acid, RAR agonism). For topical cosmetic use systemic exposure is low but measurable; regulatory actions in the EU are moving to limit vitamin A equivalents in cosmetics and require labelling, reflecting concern over systemic exposure. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8884871/))
- retinyl palmitate est-il sûr pendant l'allaitement ?
- Mechanism and animal developmental data apply equally to lactation concerns because retinoids can be systemically available and transfer to offspring via milk when internal dose is sufficient; topical use gives low but measurable absorption so breastfeeding exposure is possible though expected to be low for normal cosmetic use. Regulatory guidance and safety reviews therefore treat vitamin A derivatives cautiously in pregnancy/lactation. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8884871/))
- retinyl palmitate est-il sûr pour la peau de bébé ?
- Do not change hazard or mechanism absent infant‑specific hazard data, but exposure is increased for infants (0–3 yr) because immature skin has higher permeability and greater surface‑area‑to‑weight; therefore exposure score is raised by +1 relative to adults. Animal developmental/teratogenic data indicate intrinsic hazard of the retinoid pathway; topical exposure to infants would warrant caution. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8884871/))
- Comment VeriMom évalue-t-il retinyl palmitate ?
- VeriMom évalue retinyl palmitate à 13/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à retinyl palmitate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à retinyl palmitate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.