VeriMomDois-je éviter retinyl hydroxypentanoatyl shikimate pendant la grossesse ? | VeriMom
No specific harmonised classification or EU Annex II/III listing was located for the exact name "retinyl hydroxypentanoatyl shikimate." However, it is a retinyl ester derivative (parent = retinol/retinyl esters). The EU has restricted retinol and specific retinyl esters because of reproductive concern (SCCS / EU Regulation 2024/996 — retinoids regulated as reproductive toxicants; retinyl esters are treated as contributing to retinol equivalent exposure). By the source‑priority rules this is a class‑based concern (structural alert/read‑across), so pregnancy hazard is flagged at h=1. Mechanistically conversion of esters → retinol → retinoic acid is plausible (theoretical/demonstrated in related retinyl esters), so m=1. Topical cosmetics give low but measurable systemic exposure in typical use; therefore exposure e=1 for pregnancy. Sources: SCCS opinion on vitamin A in cosmetics and EU restriction on retinoids; animal developmental data exist for retinyl palmitate in registrations used as read‑across for the class.
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Pregnancy-safe ingredients that serve a similar function:
FAQ
- retinyl hydroxypentanoatyl shikimate est-il sûr pendant la grossesse ?
- No specific harmonised classification or EU Annex II/III listing was located for the exact name "retinyl hydroxypentanoatyl shikimate." However, it is a retinyl ester derivative (parent = retinol/retinyl esters). The EU has restricted retinol and specific retinyl esters because of reproductive concern (SCCS / EU Regulation 2024/996 — retinoids regulated as reproductive toxicants; retinyl esters are treated as contributing to retinol equivalent exposure). By the source‑priority rules this is a class‑based concern (structural alert/read‑across), so pregnancy hazard is flagged at h=1. Mechanistically conversion of esters → retinol → retinoic acid is plausible (theoretical/demonstrated in related retinyl esters), so m=1. Topical cosmetics give low but measurable systemic exposure in typical use; therefore exposure e=1 for pregnancy. Sources: SCCS opinion on vitamin A in cosmetics and EU restriction on retinoids; animal developmental data exist for retinyl palmitate in registrations used as read‑across for the class.
- retinyl hydroxypentanoatyl shikimate est-il sûr pendant l'allaitement ?
- Same rationale as pregnancy: no direct harmonised listing for this exact compound, but it is a retinyl ester derivative and therefore carries the class‑based concern. Mechanistic pathway (ester → retinol → retinoic acid) supports a theoretical mechanism. Topical exposure is generally low but measurable; breastfeeding exposure is expected to be similar to pregnancy (systemic absorption low), so e=1.
- retinyl hydroxypentanoatyl shikimate est-il sûr pour la peau de bébé ?
- Do not find infant‑specific data for this exact molecule. Using the Decision rules: do not up‑grade hazard or mechanism without infant evidence. However, infant skin has higher absorption per body weight, so exposure score increases by +1 compared with adults. The parent class (retinyl esters) are restricted in the EU and SCCS commented on children (SCCS noted more restrictive considerations for young children in some contexts), supporting caution for baby skin exposure.
- Comment VeriMom évalue-t-il retinyl hydroxypentanoatyl shikimate ?
- VeriMom évalue retinyl hydroxypentanoatyl shikimate à 13/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à retinyl hydroxypentanoatyl shikimate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à retinyl hydroxypentanoatyl shikimate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.