VeriMomDois-je éviter potassium nitrate pendant la grossesse ? | VeriMom
There are animal and mechanistic data linking nitrate/nitrite exposure to adverse prenatal outcomes at high doses (methemoglobinemia, inflammation, DNA damage and possible endocrine-related effects), and multiple supplier safety data sheets list H361 (suspected of damaging fertility/unborn child) although that appears to reflect CLP notifications/self-classifications rather than an EU harmonised Annex VI entry; therefore reproductive hazard is scored as 'suspected' (h=2). Evidence for mechanism (methemoglobinemia/nitrite conversion and inflammatory/DNA effects) is documented in a recent scoping review and older JECFA/INCHEN summaries. Topical cosmetic use is unlikely to give meaningful systemic nitrate exposure (low dermal uptake of inorganic salts) so exposure from normal cosmetic application is scored low/negligible (e=0). (Sources: PubMed scoping review; JECFA/INCHEN nitrate summary; ECHA substance/registration pages; representative SDSs and EWG entry.)
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- potassium nitrate est-il sûr pendant la grossesse ?
- There are animal and mechanistic data linking nitrate/nitrite exposure to adverse prenatal outcomes at high doses (methemoglobinemia, inflammation, DNA damage and possible endocrine-related effects), and multiple supplier safety data sheets list H361 (suspected of damaging fertility/unborn child) although that appears to reflect CLP notifications/self-classifications rather than an EU harmonised Annex VI entry; therefore reproductive hazard is scored as 'suspected' (h=2). Evidence for mechanism (methemoglobinemia/nitrite conversion and inflammatory/DNA effects) is documented in a recent scoping review and older JECFA/INCHEN summaries. Topical cosmetic use is unlikely to give meaningful systemic nitrate exposure (low dermal uptake of inorganic salts) so exposure from normal cosmetic application is scored low/negligible (e=0). (Sources: PubMed scoping review; JECFA/INCHEN nitrate summary; ECHA substance/registration pages; representative SDSs and EWG entry.)
- potassium nitrate est-il sûr pendant l'allaitement ?
- Potential reproductive/developmental concern is the same as for pregnancy (animal evidence and mechanistic pathways via nitrate→nitrite/methemoglobinemia), so hazard is 'suspected' (h=2) and mechanism retained (m=2). Dermal cosmetic use in the lactating parent is unlikely to produce significant systemic levels to transfer via breastmilk, so exposure from typical topical cosmetic use is scored negligible (e=0).
- potassium nitrate est-il sûr pour la peau de bébé ?
- No infant-specific toxicology demonstrating greater hazard was found, so hazard and mechanism remain as for adults (h=2, m=2). However, infant skin has higher surface-area-to-weight and an immature barrier, and while potassium nitrate is an inorganic, water‑soluble salt with low dermal penetration, the baby exposure score is increased by +1 relative to adults to reflect greater per‑kg exposure potential from topical application (e=1).
- Comment VeriMom évalue-t-il potassium nitrate ?
- VeriMom évalue potassium nitrate à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à potassium nitrate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à potassium nitrate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.