VeriMomDois-je éviter p-chlorophenol pendant la grossesse ? | VeriMom
Animal reproductive/developmental effects have been reported for monochlorophenols (including 4‑chlorophenol) in repeated dosing studies (ATSDR review of chlorophenols; REACH registration data note reproductive endpoints), so this meets 'suspected' (H361-style) concern but there is no harmonised H360 (confirmed human teratogen) or high‑quality human pregnancy data. Mechanistically there is not a well‑characterized reproductive mode-of-action for 4‑chlorophenol (hence a low/theoretical mechanism score). Dermal/topical exposure is plausible (low–measurable absorption given low molecular weight and log Pow ~2.4) so exposure from cosmetics is judged low but measurable for adults.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- p-chlorophenol est-il sûr pendant la grossesse ?
- Animal reproductive/developmental effects have been reported for monochlorophenols (including 4‑chlorophenol) in repeated dosing studies (ATSDR review of chlorophenols; REACH registration data note reproductive endpoints), so this meets 'suspected' (H361-style) concern but there is no harmonised H360 (confirmed human teratogen) or high‑quality human pregnancy data. Mechanistically there is not a well‑characterized reproductive mode-of-action for 4‑chlorophenol (hence a low/theoretical mechanism score). Dermal/topical exposure is plausible (low–measurable absorption given low molecular weight and log Pow ~2.4) so exposure from cosmetics is judged low but measurable for adults.
- p-chlorophenol est-il sûr pendant l'allaitement ?
- Because reproductive/developmental effects are reported in animal studies, the residue/transfer concern for breast‑fed infants is classified as 'suspected' (consistent with H361–level evidence). There are no specific lactation/milk‑transfer studies for 4‑chlorophenol identified in authoritative reviews. Expected systemic exposure from typical topical cosmetic use is low but measurable, so exposure to nursing infants via maternal systemic absorption is possible but likely low.
- p-chlorophenol est-il sûr pour la peau de bébé ?
- The hazard score remains 'suspected' based on the same animal reproductive/developmental data (no infant‑specific evidence to upscore hazard). Mechanistic evidence is limited. Exposure score is increased by +1 for baby skin (per your rules) because 4‑chlorophenol has physicochemical properties (low MW, log Pow ~2.39) consistent with measurable dermal absorption — infants have increased skin permeability and surface‑area‑to‑weight, so exposure from topical use on 0–3 yr skin is moderate/greater than adult.
- Comment VeriMom évalue-t-il p-chlorophenol ?
- VeriMom évalue p-chlorophenol à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à p-chlorophenol pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à p-chlorophenol basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.