VeriMomDois-je éviter oxyquinoline pendant la grossesse ? | VeriMom
Quinolin-8-ol (oxyquinoline, CAS 148-24-3) has an EU harmonised classification as a reproductive toxicant (Repr. 1B — H360D: “may damage the unborn child”), which by your scoring rules requires h=3. Mechanistic data linking a specific reproductive pathway are limited (mutagenicity was reported in some assays but no well‑characterised developmental mechanism), so m is scored 1 (theoretical/limited). For typical topical cosmetic use (used at ≤1% in formulations per CIR), dermal uptake is plausible but not high, so exposure (e) for pregnancy is scored 1 (low but measurable). (Sources: ECHA/EUR‑Lex harmonised classification; CIR safety assessment.).
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- oxyquinoline est-il sûr pendant la grossesse ?
- Quinolin-8-ol (oxyquinoline, CAS 148-24-3) has an EU harmonised classification as a reproductive toxicant (Repr. 1B — H360D: “may damage the unborn child”), which by your scoring rules requires h=3. Mechanistic data linking a specific reproductive pathway are limited (mutagenicity was reported in some assays but no well‑characterised developmental mechanism), so m is scored 1 (theoretical/limited). For typical topical cosmetic use (used at ≤1% in formulations per CIR), dermal uptake is plausible but not high, so exposure (e) for pregnancy is scored 1 (low but measurable). (Sources: ECHA/EUR‑Lex harmonised classification; CIR safety assessment.).
- oxyquinoline est-il sûr pendant l'allaitement ?
- Because the substance has a harmonised Repr.1B/H360D classification (systemic reproductive hazard), the hazard to nursing is scored h=3 under your rules. There is no clear, well‑established mechanism specific to lactational transfer (m=1). Dermal cosmetic use gives low but potentially measurable systemic exposure (e=1), so transfer into milk cannot be excluded at trace levels; no robust human milk data were found in the reviewed sources.
- oxyquinoline est-il sûr pour la peau de bébé ?
- Do not increase hazard or mechanism absent infant‑specific data, so h=3 and m=1 as above. Because infant skin has higher permeability and surface‑area‑to‑weight, exposure score is increased by +1 from adult (adult e=1 → infant e=2), meaning moderate concern for systemic uptake from topical application to infant skin. No infant‑specific toxicokinetic or outcome studies were identified.
- Comment VeriMom évalue-t-il oxyquinoline ?
- VeriMom évalue oxyquinoline à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à oxyquinoline pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à oxyquinoline basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.