Dois-je éviter nicotiana tabacum leaf oil pendant la grossesse ? | VeriMom
EU regulatory and ECHA data show tobacco extracts (84961-66-0) contain nicotine and registrants/notifications classify the substance for acute toxicity; nicotine has an EU harmonised classification (see ECHA) and is listed in Annex II (prohibited in cosmetics), therefore pregnancy hazard is 'suspected' (h=2). Mechanistically, nicotine is a demonstrated reproductive toxicant that crosses the placenta and has developmental effects in animal/human exposure contexts (m=2). Dermal exposure from cosmetics is plausible because nicotine is readily absorbed through skin (transdermal patches demonstrate systemic delivery), so exposure from topical products is moderate (e=2). Sources: ECHA tobacco extract and nicotine pages, CosIng entry, and clinical/pharmacokinetic studies on transdermal absorption and nicotine transfer to fetus/breastmilk.
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FAQ
- nicotiana tabacum leaf oil est-il sûr pendant la grossesse ?
- EU regulatory and ECHA data show tobacco extracts (84961-66-0) contain nicotine and registrants/notifications classify the substance for acute toxicity; nicotine has an EU harmonised classification (see ECHA) and is listed in Annex II (prohibited in cosmetics), therefore pregnancy hazard is 'suspected' (h=2). Mechanistically, nicotine is a demonstrated reproductive toxicant that crosses the placenta and has developmental effects in animal/human exposure contexts (m=2). Dermal exposure from cosmetics is plausible because nicotine is readily absorbed through skin (transdermal patches demonstrate systemic delivery), so exposure from topical products is moderate (e=2). Sources: ECHA tobacco extract and nicotine pages, CosIng entry, and clinical/pharmacokinetic studies on transdermal absorption and nicotine transfer to fetus/breastmilk.
- nicotiana tabacum leaf oil est-il sûr pendant l'allaitement ?
- Nicotine is known to be excreted into breast milk and breastfed infants are exposed when the mother uses nicotine-containing products; because tobacco extracts contain nicotine and nicotine has harmonised reproductive classification, breastfeeding is a suspected hazard (h=2). Mechanism: demonstrated transfer into milk and pharmacologic effects on infants (m=2). Exposure from topical use is measurable (transdermal absorption evidence), so breastfeeding exposure is assessed as moderate (e=2).
- nicotiana tabacum leaf oil est-il sûr pour la peau de bébé ?
- Hazard remains 'suspected' (h=2) because the extract contains nicotine (harmonised reproductive concern / EU prohibition for nicotine). Mechanism same (nicotine systemic/ developmental effects) (m=2). Exposure score increased for baby skin: infants have higher surface-area-to-weight and thinner barrier, and nicotine is transdermally absorbable (patch data); therefore exposure is elevated (adult e=2 → baby e=3).
- Comment VeriMom évalue-t-il nicotiana tabacum leaf oil ?
- VeriMom évalue nicotiana tabacum leaf oil à 33/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à nicotiana tabacum leaf oil pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à nicotiana tabacum leaf oil basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.