Dois-je éviter methyl acetamide pendant la grossesse ? | VeriMom
ECHA has a harmonised Classification & Labelling entry for N‑methylacetamide (CAS 79‑16‑3) as Repr.1B H360D (“May damage the unborn child”), which is a legally binding EU classification indicating developmental toxicity — by your calibration H360 → h=3. There is no well‑characterized molecular mechanism in the regulatory summaries, so mechanism is scored as theoretical/limited evidence (m=1). Dermal/topical systemic exposure data for cosmetic uses are not available in the regulatory summaries, so exposure from cosmetics is scored as low but measurable (e=1). (Sources: ECHA harmonised classification and ECHA substance profile; PubChem regulatory summary).
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- methyl acetamide est-il sûr pendant la grossesse ?
- ECHA has a harmonised Classification & Labelling entry for N‑methylacetamide (CAS 79‑16‑3) as Repr.1B H360D (“May damage the unborn child”), which is a legally binding EU classification indicating developmental toxicity — by your calibration H360 → h=3. There is no well‑characterized molecular mechanism in the regulatory summaries, so mechanism is scored as theoretical/limited evidence (m=1). Dermal/topical systemic exposure data for cosmetic uses are not available in the regulatory summaries, so exposure from cosmetics is scored as low but measurable (e=1). (Sources: ECHA harmonised classification and ECHA substance profile; PubChem regulatory summary).
- methyl acetamide est-il sûr pendant l'allaitement ?
- The harmonised Repr.1B / H360D classification applies to developmental toxicity and is the governing regulatory flag for reproductive/developmental hazard and therefore is applied for lactation context as well (h=3). No specific mechanistic or lactation transfer studies were identified in the searched authoritative databases (m=1). No quantitative dermal absorption or milk‑transfer data were found for cosmetic use; systemic exposure from topical use is assumed low but measurable (e=1).
- methyl acetamide est-il sûr pour la peau de bébé ?
- Because the substance carries a harmonised H360D classification (developmental toxicant; Repr.1B) the hazard score is h=3 per your calibration. Mechanistic information is limited (m=1). For exposure, infant skin has higher absorption; in the absence of dermal absorption data for cosmetic formulations, increase exposure by +1 for baby skin (adult e=1 → baby e=2). No infant‑specific safety data were located. (Sources: ECHA harmonised CLP; ECHA substance information; PubChem.)
- Comment VeriMom évalue-t-il methyl acetamide ?
- VeriMom évalue methyl acetamide à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à methyl acetamide pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à methyl acetamide basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.