VeriMomDois-je éviter methoxyethanol acetate pendant la grossesse ? | VeriMom
Harmonised CLP classification for 2‑methoxyethyl acetate (CAS 110‑49‑6) is Repr. 1B, H360FD (harmonised Annex VI), therefore per your calibration this is h=3. The compound is known to be metabolised to 2‑methoxyethanol (EGME), which has demonstrated reproductive toxicity in animals and occupational settings (mechanism via the glycol‑ether metabolites is established), so mechanism is scored 2. Dermal absorption is documented as measurable for glycol ether esters, so topical exposure is low but measurable (e=1). Sources: ECHA harmonised classification and EU Cosmetic Regulation Annex II (prohibited).
ECHA regulatory hazard statements
- •H360FD
What to use instead
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FAQ
- methoxyethanol acetate est-il sûr pendant la grossesse ?
- Harmonised CLP classification for 2‑methoxyethyl acetate (CAS 110‑49‑6) is Repr. 1B, H360FD (harmonised Annex VI), therefore per your calibration this is h=3. The compound is known to be metabolised to 2‑methoxyethanol (EGME), which has demonstrated reproductive toxicity in animals and occupational settings (mechanism via the glycol‑ether metabolites is established), so mechanism is scored 2. Dermal absorption is documented as measurable for glycol ether esters, so topical exposure is low but measurable (e=1). Sources: ECHA harmonised classification and EU Cosmetic Regulation Annex II (prohibited).
- methoxyethanol acetate est-il sûr pendant l'allaitement ?
- Same hazard basis applies for lactation: harmonised Repr.1B (H360FD) and metabolic conversion to EGME indicate a confirmed reproductive hazard potential for mother/infant exposure (h=3). Mechanistic evidence of metabolite‑mediated toxicity supports m=2. For topical use, dermal uptake is measurable but not high (e=1); data on milk transfer are limited but given systemic absorption and classification concern, lactational exposure is plausible and caution is warranted.
- methoxyethanol acetate est-il sûr pour la peau de bébé ?
- Hazard remains h=3 because of harmonised H360FD. Mechanistic concerns (metabolic conversion to EGME) remain (m=2). Exposure is increased for infants (per your rule +1) because infant skin has higher absorption/SA:weight and the parent compound is dermally absorbable — adult e=1 → baby e=2. The substance is explicitly prohibited in cosmetics under EU Cosmetic Regulation Annex II, so it should not be present in products for infants/children.
- Comment VeriMom évalue-t-il methoxyethanol acetate ?
- VeriMom évalue methoxyethanol acetate à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à methoxyethanol acetate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à methoxyethanol acetate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.