VeriMomDois-je éviter melamine pendant la grossesse ? | VeriMom
Melamine (CAS 108-78-1) is flagged by ECHA/REACH processes (candidate SVHC; SDSs/ECHA listings show H361f in some notices) and animal studies report embryo/fetotoxic and reproductive effects at high oral doses in rodents, so it meets “suspected” reproductive hazard (H361-level). Mechanistic work (rodent and in vitro studies) shows effects on oocytes, placental/fetal growth and increased apoptosis, supporting a demonstrated mechanism. Dermal/topical exposure from cosmetics is expected to give low but measurable systemic exposure (dermal absorption described as poor in some assessments but not zero), so exposure score is low (1). Sources: ECHA listing, Canada/ECCC human-health update, NTP and peer-reviewed developmental/reproductive studies.
ECHA regulatory hazard statements
- •H351
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- melamine est-il sûr pendant la grossesse ?
- Melamine (CAS 108-78-1) is flagged by ECHA/REACH processes (candidate SVHC; SDSs/ECHA listings show H361f in some notices) and animal studies report embryo/fetotoxic and reproductive effects at high oral doses in rodents, so it meets “suspected” reproductive hazard (H361-level). Mechanistic work (rodent and in vitro studies) shows effects on oocytes, placental/fetal growth and increased apoptosis, supporting a demonstrated mechanism. Dermal/topical exposure from cosmetics is expected to give low but measurable systemic exposure (dermal absorption described as poor in some assessments but not zero), so exposure score is low (1). Sources: ECHA listing, Canada/ECCC human-health update, NTP and peer-reviewed developmental/reproductive studies.
- melamine est-il sûr pendant l'allaitement ?
- Same hazard and mechanism rationale as pregnancy (animal reproductive and perinatal effects; mechanistic studies). For topical cosmetic use systemic levels are expected to be low but measurable, so breastmilk transfer potential is low but possible—exposure scored 1 in absence of specific lactation transfer data.
- melamine est-il sûr pour la peau de bébé ?
- Hazard and mechanistic evidence come from the same animal and in vitro literature and support ‘suspected’ reproductive/developmental toxicity. Dermal exposure for infants is assigned one tier higher than adults because infant skin is more permeable; therefore exposure is increased to 2 (moderate) if the ingredient has measurable absorption. There is no infant-specific toxicokinetic evidence to change hazard/mechanism scores.
- Comment VeriMom évalue-t-il melamine ?
- VeriMom évalue melamine à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à melamine pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à melamine basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.