VeriMomDois-je éviter isopropylparaben pendant la grossesse ? | VeriMom
Isopropylparaben (isopropyl 4‑hydroxybenzoate, CAS 4191‑73‑5) is restricted/prohibited in the EU for cosmetics (Annex II of Regulation 1223/2009), reflecting regulatory concern about certain higher alkyl parabens and reproductive/ endocrine effects. There are in vitro reports of estrogenic activity for some parabens (isopropylparaben reported as relatively active in some screens) and animal toxicity dossiers on ECHA; taken together this supports a 'suspected' reproductive/ developmental concern (h=2) and a demonstrated in vitro endocrine mechanism (m=2). Topical cosmetic use gives low but measurable systemic exposure (e=1). Sources: EU Annex II (cosmetics), ECHA registration dossier, peer‑reviewed and review sources listed below.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- isopropylparaben est-il sûr pendant la grossesse ?
- Isopropylparaben (isopropyl 4‑hydroxybenzoate, CAS 4191‑73‑5) is restricted/prohibited in the EU for cosmetics (Annex II of Regulation 1223/2009), reflecting regulatory concern about certain higher alkyl parabens and reproductive/ endocrine effects. There are in vitro reports of estrogenic activity for some parabens (isopropylparaben reported as relatively active in some screens) and animal toxicity dossiers on ECHA; taken together this supports a 'suspected' reproductive/ developmental concern (h=2) and a demonstrated in vitro endocrine mechanism (m=2). Topical cosmetic use gives low but measurable systemic exposure (e=1). Sources: EU Annex II (cosmetics), ECHA registration dossier, peer‑reviewed and review sources listed below.
- isopropylparaben est-il sûr pendant l'allaitement ?
- Same hazard and mechanism considerations as pregnancy (suspected reproductive/endocrine activity). There are no robust human lactation studies showing clear transfer or infant effects; however parabens can be systemically absorbed after topical use at low levels, so breastfeeding exposure is considered low but measurable (e=1). Regulatory prohibition in cosmetics supports caution for lactating people.
- isopropylparaben est-il sûr pour la peau de bébé ?
- Hazard and mechanism scores follow adult reproductive assessment (suspected endocrine/reproductive concern; in vitro activity). Exposure (e) is increased by +1 for infants (0–3 yr) because immature barrier and higher surface‑area‑to‑weight make percutaneous absorption and systemic dose relatively higher; thus e=2. Note: there are few infant‑specific toxicology studies for isopropylparaben, but regulatory bans on this paraben class in the EU for leave‑on/rinse‑off cosmetic uses indicate a conservative approach for infant products.
- Comment VeriMom évalue-t-il isopropylparaben ?
- VeriMom évalue isopropylparaben à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à isopropylparaben pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à isopropylparaben basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.