VeriMomDois-je éviter imidazole pendant la grossesse ? | VeriMom
Imidazole (CAS 288-32-4) is listed by ECHA with a harmonised classification for developmental toxicity (Category 1B, H360D), which by your scoring rules is H360-level evidence -> h=3. The mechanistic basis for the classification is not well‐characterised in publicly available dossiers, so mechanism is scored as theoretical/uncertain (m=1). Dermal/topical cosmetic exposure would likely give low but measurable systemic exposure for an adult (e=1) unless formulation/route increases uptake; this is supported by ECHA/EU classification and multiple safety data sheets listing H360D.
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- imidazole est-il sûr pendant la grossesse ?
- Imidazole (CAS 288-32-4) is listed by ECHA with a harmonised classification for developmental toxicity (Category 1B, H360D), which by your scoring rules is H360-level evidence -> h=3. The mechanistic basis for the classification is not well‐characterised in publicly available dossiers, so mechanism is scored as theoretical/uncertain (m=1). Dermal/topical cosmetic exposure would likely give low but measurable systemic exposure for an adult (e=1) unless formulation/route increases uptake; this is supported by ECHA/EU classification and multiple safety data sheets listing H360D.
- imidazole est-il sûr pendant l'allaitement ?
- Because imidazole has a harmonised developmental/teratogenic classification (H360D, Category 1B) the hazard for lactation/breastfeeding is elevated and scored h=3 per your rule for H360-level evidence. No specific human milk transfer or breastfeeding studies were identified in the sources consulted, so mechanistic evidence is limited (m=1). Maternal topical use would most likely give low but measurable systemic exposure (e=1) in adults; therefore potential transfer in milk cannot be excluded.
- imidazole est-il sûr pour la peau de bébé ?
- Hazard remains H360-level (h=3) because of ECHA harmonised developmental classification. Mechanistic data are limited (m=1). For baby skin (0–3 yr) exposure scoring increases by +1 compared with adults when the adult exposure is measurable: adult e=1 -> infant e=2 because infant skin has higher surface-area-to-weight and an immature barrier, increasing potential absorption.
- Comment VeriMom évalue-t-il imidazole ?
- VeriMom évalue imidazole à 27/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à imidazole pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à imidazole basée sur une fonction similaire et une classification sans risques connus.
Vérifiez chaque étiquette en 2 secondes
Obtenez VeriMom gratuitement — scannez n'importe quel produit et voyez le score de sécurité grossesse instantanément.
Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.