VeriMomDois-je éviter hydroxycortisone succinate pendant la grossesse ? | VeriMom
EU/ECHA substance information shows harmonised classification for reproductive toxicity (Repr. 1A H360 and Repr.2 H361) for hydrocortisone 21‑hemisuccinate (CAS 2203-97-6), so this meets the criterion for confirmed reproductive hazard (h=3). The mechanism is glucocorticoid action with demonstrated ability of systemic corticosteroids to affect fetal development/placenta (m=2). For typical topical cosmetic use, systemic absorption is low (e=1), so exposure from normal topical cosmetic use is expected to be low but not zero. (Sources: ECHA brief profile / C&L inventory; guidance on topical corticosteroids in pregnancy).
ECHA regulatory hazard statements
- •H360
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- hydroxycortisone succinate est-il sûr pendant la grossesse ?
- EU/ECHA substance information shows harmonised classification for reproductive toxicity (Repr. 1A H360 and Repr.2 H361) for hydrocortisone 21‑hemisuccinate (CAS 2203-97-6), so this meets the criterion for confirmed reproductive hazard (h=3). The mechanism is glucocorticoid action with demonstrated ability of systemic corticosteroids to affect fetal development/placenta (m=2). For typical topical cosmetic use, systemic absorption is low (e=1), so exposure from normal topical cosmetic use is expected to be low but not zero. (Sources: ECHA brief profile / C&L inventory; guidance on topical corticosteroids in pregnancy).
- hydroxycortisone succinate est-il sûr pendant l'allaitement ?
- Because of the harmonised reproductive classification for the substance (see ECHA) and the known systemic effects of hydrocortisone, a conservative approach assigns h=3 for lactation context as well. Mechanistically, corticosteroids can distribute systemically and small amounts can appear in milk (m=2). For topical cosmetic application (not systemic therapy), milk exposure is generally low unless applied directly to the breast/nipple (e=1). (Sources: ECHA C&L brief profile; LactMed and NHS topical corticosteroid guidance).
- hydroxycortisone succinate est-il sûr pour la peau de bébé ?
- Harmonised classification (ECHA) indicates reproductive hazard (h=3) for the substance; that harmonised CMR classification applies as the primary hazard signal. Mechanism remains hydrocortisone (glucocorticoid) activity (m=2). Dermal exposure and systemic uptake from baby skin are higher than adult per surface‑area‑to‑weight and immature barrier — therefore exposure score is increased by +1 versus adult topical use (adult e=1 → infant e=2). There is no infant‑specific innocuousness data for cosmetic use of this specific derivative. (Sources: ECHA brief profile; EDF/dermatology and guideline reviews on topical corticosteroids/pregnancy and child skin).
- Comment VeriMom évalue-t-il hydroxycortisone succinate ?
- VeriMom évalue hydroxycortisone succinate à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à hydroxycortisone succinate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à hydroxycortisone succinate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.