VeriMomDois-je éviter ethyl pyrrolidone pendant la grossesse ? | VeriMom
N‑ethyl‑2‑pyrrolidone (NEP; CAS 2687‑91‑4) has a harmonised CLP classification Repr. 1B H360D (may damage the unborn child) in ECHA/EU documents, which mandates a high hazard score. Animal studies report developmental toxicity after oral dosing, and toxicokinetic data show placental/fetal exposure in rats. Topical cosmetic exposure would likely give low but measurable systemic absorption for an organic solvent, so exposure is scored as 1. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ethyl pyrrolidone est-il sûr pendant la grossesse ?
- N‑ethyl‑2‑pyrrolidone (NEP; CAS 2687‑91‑4) has a harmonised CLP classification Repr. 1B H360D (may damage the unborn child) in ECHA/EU documents, which mandates a high hazard score. Animal studies report developmental toxicity after oral dosing, and toxicokinetic data show placental/fetal exposure in rats. Topical cosmetic exposure would likely give low but measurable systemic absorption for an organic solvent, so exposure is scored as 1. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
- ethyl pyrrolidone est-il sûr pendant l'allaitement ?
- Because NEP carries harmonised Repr. 1B H360D classification and shows demonstrated systemic and placental transfer in animal studies, the hazard for lactation is aligned with pregnancy (h=3). Mechanistic/tk data show systemic availability and metabolites in dam urine/blood; breastmilk transfer is not well characterized in humans but systemic presence supports potential exposure to nursing infants, so exposure is rated low but measurable for topical use. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
- ethyl pyrrolidone est-il sûr pour la peau de bébé ?
- Hazard and mechanism remain driven by the harmonised Repr. 1B classification and animal developmental/toxicokinetic data (h=3, m=2). Because infant skin (0–3 yr) has higher permeability and higher surface‑area‑to‑weight, exposure is increased by +1 relative to adults (adult e=1 → infant e=2) when there is measurable absorption. No infant‑specific safety data were found. ([echa.europa.eu](https://echa.europa.eu/documents/10162/380057b0-53a7-178a-3c2a-6fdf32826fe3?utm_source=openai))
- Comment VeriMom évalue-t-il ethyl pyrrolidone ?
- VeriMom évalue ethyl pyrrolidone à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à ethyl pyrrolidone pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à ethyl pyrrolidone basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.