VeriMomDois-je éviter epichlorohydrin pendant la grossesse ? | VeriMom
Animal developmental and reproductive toxicity studies (one-generation and developmental studies) report adverse effects; ECHA registration dossier and EPA summaries document these findings and some C&L notifications list H361 (suspected reproductive toxicant). There is mechanistic evidence that epichlorohydrin is a reactive epoxide (genotoxic/alkylating) which plausibly underlies developmental/reproductive toxicity. Topical cosmetic exposure would be low but measurable; epichlorohydrin has a skin penetration (NIOSH skin notation) so systemic exposure is possible if used on skin. (Sources: ECHA registration dossier; PubMed study; EPA summary; NIOSH/NIOSH PEL page).
ECHA regulatory hazard statements
- •H350
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- epichlorohydrin est-il sûr pendant la grossesse ?
- Animal developmental and reproductive toxicity studies (one-generation and developmental studies) report adverse effects; ECHA registration dossier and EPA summaries document these findings and some C&L notifications list H361 (suspected reproductive toxicant). There is mechanistic evidence that epichlorohydrin is a reactive epoxide (genotoxic/alkylating) which plausibly underlies developmental/reproductive toxicity. Topical cosmetic exposure would be low but measurable; epichlorohydrin has a skin penetration (NIOSH skin notation) so systemic exposure is possible if used on skin. (Sources: ECHA registration dossier; PubMed study; EPA summary; NIOSH/NIOSH PEL page).
- epichlorohydrin est-il sûr pendant l'allaitement ?
- Same rationale as for pregnancy: animal data and regulatory dossiers indicate reproductive/developmental hazard (H361 notifications). Mechanistic genotoxic/reactive epoxide activity supports potential for systemic harm. Dermal absorption is possible so measurable maternal systemic exposure (and therefore theoretical transfer to breastmilk) cannot be excluded, though direct lactation-specific data are unavailable.
- epichlorohydrin est-il sûr pour la peau de bébé ?
- Hazard and mechanism same as adults (animal reproductive/developmental effects; reactive epoxide chemistry). Because epichlorohydrin is skin-penetrant (NIOSH skin notation) and infant skin has higher surface-area-to-weight and immature barrier, exposure score is increased by +1 (adult e=1 → infant e=2). There are no infant-specific safety studies identified.
- Comment VeriMom évalue-t-il epichlorohydrin ?
- VeriMom évalue epichlorohydrin à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à epichlorohydrin pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à epichlorohydrin basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.