Dois-je éviter diethylhexyl phthalate pendant la grossesse ? | VeriMom
DEHP (CAS 117-81-7) has a harmonised CLP classification H360FD (may damage fertility; may damage the unborn child) under ECHA/Annex VI, which by calibration mandates h=3. Mechanistically, DEHP and its primary metabolite MEHP cause well-characterised anti-androgenic and developmental effects in multiple animal studies and alter placental development, supporting m=3. Because DEHP is prohibited from use in cosmetic products under the EU Cosmetics Regulation (Annex II), topical cosmetic exposure during pregnancy should be negligible (e=0) for cosmetic-grade use; however systemic exposures from other sources (medical devices, contaminated food, dust) remain relevant but are outside 'cosmetic use' exposure scoring.
ECHA regulatory hazard statements
- •H360FD
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- diethylhexyl phthalate est-il sûr pendant la grossesse ?
- DEHP (CAS 117-81-7) has a harmonised CLP classification H360FD (may damage fertility; may damage the unborn child) under ECHA/Annex VI, which by calibration mandates h=3. Mechanistically, DEHP and its primary metabolite MEHP cause well-characterised anti-androgenic and developmental effects in multiple animal studies and alter placental development, supporting m=3. Because DEHP is prohibited from use in cosmetic products under the EU Cosmetics Regulation (Annex II), topical cosmetic exposure during pregnancy should be negligible (e=0) for cosmetic-grade use; however systemic exposures from other sources (medical devices, contaminated food, dust) remain relevant but are outside 'cosmetic use' exposure scoring.
- diethylhexyl phthalate est-il sûr pendant l'allaitement ?
- Harmonised H360FD classification and abundant animal data showing reproductive/developmental toxicity and endocrine disruption justify h=3 and m=3 for breastfeeding context. DEHP has been shown to transfer and produce metabolites that are biologically active; although breastmilk transfer and infant internal dose are described in the literature for environmental exposures, cosmetic topical use in the EU is banned so cosmetic-source exposure is expected to be negligible (e=0).
- diethylhexyl phthalate est-il sûr pour la peau de bébé ?
- Because DEHP is harmonised as H360FD (CMR Category 1B) the hazard to infants is scored h=3 by calibration. Mechanistic data (anti-androgenic effects, endocrine disruption, developmental effects in rodents) support m=3. For cosmetic topical use, DEHP is listed in EU Annex II (prohibited), so exposure from cosmetics is expected to be negligible (e=0). If DEHP were present in a formulation (e.g., contamination or in non‑EU markets), infant skin has higher absorption potential and the exposure score would be higher — but that scenario is outside compliant cosmetic use.
- Comment VeriMom évalue-t-il diethylhexyl phthalate ?
- VeriMom évalue diethylhexyl phthalate à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à diethylhexyl phthalate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à diethylhexyl phthalate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.