Dois-je éviter dibutyl phthalate pendant la grossesse ? | VeriMom
Dibutyl phthalate (DBP, CAS 84-74-2) has a harmonised CLP classification as H360 (may damage fertility or the unborn child) and is listed in the EU cosmetics Annex II (prohibited), indicating confirmed reproductive hazard; animal studies show male reproductive/developmental effects consistent with anti-androgenic mechanisms. (ECHA harmonised classification and Annex II listing; CIR and peer-reviewed animal literature support mechanism). Sources: https://echa.europa.eu/ (DBP brief/profile and C&L Annex VI harmonised H360), https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic
ECHA regulatory hazard statements
- •H360DF
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- dibutyl phthalate est-il sûr pendant la grossesse ?
- Dibutyl phthalate (DBP, CAS 84-74-2) has a harmonised CLP classification as H360 (may damage fertility or the unborn child) and is listed in the EU cosmetics Annex II (prohibited), indicating confirmed reproductive hazard; animal studies show male reproductive/developmental effects consistent with anti-androgenic mechanisms. (ECHA harmonised classification and Annex II listing; CIR and peer-reviewed animal literature support mechanism). Sources: https://echa.europa.eu/ (DBP brief/profile and C&L Annex VI harmonised H360), https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic
- dibutyl phthalate est-il sûr pendant l'allaitement ?
- Because DBP is a harmonised H360 substance (reproductive toxicant) and has demonstrated endocrine/anti-androgenic effects in animals, it is scored high for hazard and mechanism. DBP is lipophilic and human biomonitoring/authoritative assessments indicate systemic uptake and potential for body burden (supporting possible transfer to breastmilk), so exposure via systemic routes during lactation is rated higher than negligible. Sources: https://echa.europa.eu/brief-profile/-/briefprofile/100.001.416, https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/risk-evaluation-dibutyl-phthalate-12-benzene, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic
- dibutyl phthalate est-il sûr pour la peau de bébé ?
- Harmonised H360 applies irrespective of age (so hazard = 3). Mechanistic data (anti-androgenic/reprotoxic) are demonstrated in vivo in animals and remain relevant. For infant skin exposure, exposure score is increased by +1 relative to adult topical use because infants have higher surface-area-to-weight and more permeable skin and DBP is measurable/systemically absorbable; therefore exposure is moderate. Sources: https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://echa.europa.eu/brief-profile/-/briefprofile/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic
- Comment VeriMom évalue-t-il dibutyl phthalate ?
- VeriMom évalue dibutyl phthalate à 13/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à dibutyl phthalate pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à dibutyl phthalate basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.