VeriMomDois-je éviter chlorophene pendant la grossesse ? | VeriMom
Chlorophene (clorofene, CAS 120-32-1) has a harmonised CLP classification including H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). Animal studies (NTP 2‑year gavage and other toxicology reports) show developmental/non‑reproductive toxic effects (including some non‑dose‑dependent developmental findings in rabbits and mutagenicity in vitro), supporting a demonstrated mechanistic concern (m=2). For typical topical cosmetic use exposure is expected to be low but measurable (e=1). Sources: ECHA harmonised CLP listing; NTP / toxicology studies; published safety assessments. (See sources.)
ECHA regulatory hazard statements
- •H351
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- chlorophene est-il sûr pendant la grossesse ?
- Chlorophene (clorofene, CAS 120-32-1) has a harmonised CLP classification including H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). Animal studies (NTP 2‑year gavage and other toxicology reports) show developmental/non‑reproductive toxic effects (including some non‑dose‑dependent developmental findings in rabbits and mutagenicity in vitro), supporting a demonstrated mechanistic concern (m=2). For typical topical cosmetic use exposure is expected to be low but measurable (e=1). Sources: ECHA harmonised CLP listing; NTP / toxicology studies; published safety assessments. (See sources.)
- chlorophene est-il sûr pendant l'allaitement ?
- Harmonised H361 (and related regulatory assessments) indicate suspected effects on fertility/development (h=2). Mechanistic and toxicology data from animal studies and in vitro mutagenicity support a demonstrated concern (m=2). For topical use, maternal systemic exposure is expected to be low but measurable (e=1); no reliable data were found documenting transfer into breastmilk, so exposure via breastmilk cannot be ruled out. Sources: ECHA CLP listing; NTP and other toxicology literature.
- chlorophene est-il sûr pour la peau de bébé ?
- Hazard is the same (h=2) because of the harmonised H361f and supporting animal/toxicology data. Mechanistic evidence from studies (mutagenicity/in vivo toxicity) supports m=2. Exposure score is increased by +1 for baby skin (adult e=1 → baby e=2) because chlorophene is a relatively lipophilic, absorbable phenolic antimicrobial (logP ≈4.3) and infants (0–3 yrs) have higher surface‑area‑to‑weight and an immature barrier, increasing per‑kg systemic exposure from topical application. No infant‑specific toxicokinetic or dermal absorption studies were identified. Sources: ECHA CLP; NTP/toxicology studies; product/physicochemical records.
- Comment VeriMom évalue-t-il chlorophene ?
- VeriMom évalue chlorophene à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à chlorophene pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à chlorophene basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.