VeriMomDois-je éviter captan pendant la grossesse ? | VeriMom
Captan has been flagged as a suspected reproductive hazard (H361-level concern reported in regulatory dossiers and SDSs) and animal/experimental studies report effects on reproductive tissues (mouse ovarian disruption, decreased fertility in some rodent studies). Mechanistic studies show mitochondrial dysfunction, oxidative stress, DNA damage and apoptosis in oocytes (demonstrated in vivo/in vitro). For topical/cosmetic use dermal absorption is reported to be very low (<1% per hour in regulatory assessments and human toxicokinetic studies), so exposure from cosmetic topical use is low but measurable. Sources: PubMed (mouse ovarian study), EPA/NPIC summaries, human toxicokinetic/dermal studies and occupational assessments.
ECHA regulatory hazard statements
- •H351
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- captan est-il sûr pendant la grossesse ?
- Captan has been flagged as a suspected reproductive hazard (H361-level concern reported in regulatory dossiers and SDSs) and animal/experimental studies report effects on reproductive tissues (mouse ovarian disruption, decreased fertility in some rodent studies). Mechanistic studies show mitochondrial dysfunction, oxidative stress, DNA damage and apoptosis in oocytes (demonstrated in vivo/in vitro). For topical/cosmetic use dermal absorption is reported to be very low (<1% per hour in regulatory assessments and human toxicokinetic studies), so exposure from cosmetic topical use is low but measurable. Sources: PubMed (mouse ovarian study), EPA/NPIC summaries, human toxicokinetic/dermal studies and occupational assessments.
- captan est-il sûr pendant l'allaitement ?
- Hazard and mechanism same rationale as for pregnancy (animal reproductive effects and mechanistic evidence). Dermal absorption from topical application is low (human toxicokinetic data and EPA/NPIC assessments), and while captan metabolites have been detected in animal milk in some studies, human milk transfer data are sparse — exposure via maternal topical use is therefore low but measurable. Sources: NPIC/EPA summaries, human dermal toxicokinetic study, animal milk data.
- captan est-il sûr pour la peau de bébé ?
- Hazard (H361-level/suspected reproductive/developmental effects) and mechanistic findings apply (animal reproductive/ovarian effects, demonstrated oocyte toxicity). Dermal absorption for adults is low but measurable; per your scoring rules, infant skin exposure is increased by +1 because infant skin has higher permeability and higher surface-area-to-weight, so exposure for a baby (0–3 yr) is moderate. There is no infant-specific evidence to raise hazard or mechanism scores beyond the adult evidence. Sources: human dermal/tokinetic studies, EPA/NPIC, PubMed reproductive/toxicology studies.
- Comment VeriMom évalue-t-il captan ?
- VeriMom évalue captan à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à captan pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à captan basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.