VeriMomDois-je éviter basic green 4 pendant la grossesse ? | VeriMom
ECHA has a harmonised CLP entry for malachite green (Basic Green 4, CAS 569-64-2) with a reproductive/developmental suspect classification (H361d — 'suspected of damaging the unborn child'), so reproductive hazard is judged as 'suspected'. Animal and in vitro studies report developmental effects and show that the metabolite leucomalachite green (LMG) is present in dam plasma and amniotic fluid, supporting a plausible mechanism (placental exposure). Topical/cosmetic exposure would likely give low but measurable systemic exposure if used, so exposure score is 1. (ECHA Annex/CLP; rat developmental study).
ECHA regulatory hazard statements
- •H361
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- basic green 4 est-il sûr pendant la grossesse ?
- ECHA has a harmonised CLP entry for malachite green (Basic Green 4, CAS 569-64-2) with a reproductive/developmental suspect classification (H361d — 'suspected of damaging the unborn child'), so reproductive hazard is judged as 'suspected'. Animal and in vitro studies report developmental effects and show that the metabolite leucomalachite green (LMG) is present in dam plasma and amniotic fluid, supporting a plausible mechanism (placental exposure). Topical/cosmetic exposure would likely give low but measurable systemic exposure if used, so exposure score is 1. (ECHA Annex/CLP; rat developmental study).
- basic green 4 est-il sûr pendant l'allaitement ?
- Harmonised classification for developmental hazard (H361d) and animal data demonstrating maternal systemic exposure and placental/biological transfer (LMG detected in amniotic fluid) indicate suspected risk to the developing offspring; while direct human lactation studies are lacking, demonstrated maternal systemic absorption/metabolism supports a plausible mechanism for transfer into milk. Typical topical cosmetic use would likely give low but measurable maternal exposure (score 1).
- basic green 4 est-il sûr pour la peau de bébé ?
- Hazard (H361d) and animal developmental/toxicity data justify the same hazard score for infant skin exposure (do not escalate h/m without infant-specific toxicity data). Mechanistic evidence (LMG in maternal plasma/amniotic fluid) supports m=2. Because infant skin has higher absorption/surface-area-to-weight, exposure score is increased by +1 versus adult topical (adult e=1 → infant e=2). Note: the substance is listed as prohibited in EU cosmetic Annex II / disallowed in baby products in multiple lists, reflecting regulatory precaution.
- Comment VeriMom évalue-t-il basic green 4 ?
- VeriMom évalue basic green 4 à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à basic green 4 pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à basic green 4 basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.