VeriMomDois-je éviter acrolein pendant la grossesse ? | VeriMom
Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
ECHA regulatory hazard statements
- •H225
- •H330
- •H311
- •H300
- •H314
- •H400
- •H410
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- acrolein est-il sûr pendant la grossesse ?
- Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.
- acrolein est-il sûr pendant l'allaitement ?
- Same hazard and mechanism considerations apply for lactation: animal reproductive/developmental effects and mechanistic evidence indicate a suspected reproductive hazard. For cosmetic topical use systemic absorption is expected to be low but measurable, so transfer into breastmilk could theoretically occur if significant systemic levels were reached, but typical cosmetic exposures are low.
- acrolein est-il sûr pour la peau de bébé ?
- Hazard and mechanism same as for adults (suspected reproductive/developmental hazard with demonstrated mitochondrial/oocyte effects). Exposure score is increased by +1 for infants (per your rule) because acrolein has measurable dermal effects (it is skin‑corrosive/irritant and a small reactive molecule) so infants’ higher surface‑area‑to‑weight and immature barrier raise likely systemic uptake from topical application above adult levels.
- Comment VeriMom évalue-t-il acrolein ?
- VeriMom évalue acrolein à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à acrolein pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à acrolein basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.