Dois-je éviter acetyl benzoyloxy prasterone pendant la grossesse ? | VeriMom
No EU Annex II/III ban or harmonised CLP classification was found for this CAS; however the compound is a prasterone (DHEA) ester and prasterone has androgen/estrogen activity in humans (medicinal use). Steroidal hormonal activity implies suspected reproductive/developmental hazard for pregnancy (calibration: demonstrated endocrine activity → h=2). There are clinical/peer-reviewed sources describing prasterone as an active steroid. No harmonised H360/H361 or Annex II listing was found for this specific derivative. (Sources: PubMed prasterone review; INCI/Gazzetta INCI listing.)
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- acetyl benzoyloxy prasterone est-il sûr pendant la grossesse ?
- No EU Annex II/III ban or harmonised CLP classification was found for this CAS; however the compound is a prasterone (DHEA) ester and prasterone has androgen/estrogen activity in humans (medicinal use). Steroidal hormonal activity implies suspected reproductive/developmental hazard for pregnancy (calibration: demonstrated endocrine activity → h=2). There are clinical/peer-reviewed sources describing prasterone as an active steroid. No harmonised H360/H361 or Annex II listing was found for this specific derivative. (Sources: PubMed prasterone review; INCI/Gazzetta INCI listing.)
- acetyl benzoyloxy prasterone est-il sûr pendant l'allaitement ?
- Same rationale as pregnancy: the derivative can be expected to act (or be metabolised to) a steroid hormone (prasterone) with potential to reach systemic circulation; steroids may be transferred into breastmilk and affect nursing infants—this produces a suspected hazard in breastfeeding (h=2). No direct breastfeeding-specific studies on this derivative were located. (Sources: prasterone clinical literature; INCI lists.)
- acetyl benzoyloxy prasterone est-il sûr pour la peau de bébé ?
- Hazard and mechanism scores reflect the steroidal parent (prasterone) activity (suspected endocrine/reproductive hazard). Exposure score is increased for infant skin: topical steroidal molecules or esters that are measurably absorbable in adults are likely to have higher per-bodyweight exposure in infants with immature barrier function—so adult e=2 (moderate absorption expected for a lipophilic steroid-ester), infant e elevated to 3 per instructions. No infant-specific dermal studies for this compound were found. (Sources: INCI / cosmetic ingredient databases; prasterone clinical literature.)
- Comment VeriMom évalue-t-il acetyl benzoyloxy prasterone ?
- VeriMom évalue acetyl benzoyloxy prasterone à 33/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à acetyl benzoyloxy prasterone pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à acetyl benzoyloxy prasterone basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.