VeriMomDois-je éviter 2-hydroxyethyl picramic acid pendant la grossesse ? | VeriMom
ECHA lists a harmonised CLP classification for 2-hydroxyethyl picramic acid (Index No. 604-056-00-2, CAS 99610-72-7) including H361f (suspected of damaging fertility), which per EU harmonised CLP guidance is a Category 2 reproductive hazard (supports h=2). Peer-review/regulatory assessments (SCCS/CIR/IMAP/TGA summaries) report animal data and testicular effects, indicating a demonstrated reproductive mechanism (m=2). Topical exposure from hair-dye use is low but measurable (SCCS evaluated on-head limits such as 0.6% and concluded risk mainly from sensitisation), so exposure for pregnant adults from cosmetic use is assessed as low but measurable (e=1).
ECHA regulatory hazard statements
- •H361F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- 2-hydroxyethyl picramic acid est-il sûr pendant la grossesse ?
- ECHA lists a harmonised CLP classification for 2-hydroxyethyl picramic acid (Index No. 604-056-00-2, CAS 99610-72-7) including H361f (suspected of damaging fertility), which per EU harmonised CLP guidance is a Category 2 reproductive hazard (supports h=2). Peer-review/regulatory assessments (SCCS/CIR/IMAP/TGA summaries) report animal data and testicular effects, indicating a demonstrated reproductive mechanism (m=2). Topical exposure from hair-dye use is low but measurable (SCCS evaluated on-head limits such as 0.6% and concluded risk mainly from sensitisation), so exposure for pregnant adults from cosmetic use is assessed as low but measurable (e=1).
- 2-hydroxyethyl picramic acid est-il sûr pendant l'allaitement ?
- Harmonised CLP H361f applies; regulatory reviews cite reproductive toxicity in animals (m=2) and harmonised classification carries to concerns for breastfeeding parents. Topical cosmetic use gives low but measurable exposure (SCCS on-head limits), so e=1 for lactating adults. There are no specific data showing transfer into breastmilk identified in the reviewed sources (data gap).
- 2-hydroxyethyl picramic acid est-il sûr pour la peau de bébé ?
- Hazard (H361f harmonised) and reported animal reproductive/testicular effects justify h=2 for infant-related concern under the requested scoring system. Mechanistic evidence from animal reproductive toxicology supports m=2. Because infant skin (0–3 yr) has a higher surface‑area:weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → infant e=2) where topically applied products or accidental exposure could occur. No infant-specific absorption studies were found. (See data gaps.)
- Comment VeriMom évalue-t-il 2-hydroxyethyl picramic acid ?
- VeriMom évalue 2-hydroxyethyl picramic acid à 20/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à 2-hydroxyethyl picramic acid pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à 2-hydroxyethyl picramic acid basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.