¿Es tussilago farfara leaf extract seguro durante el embarazo?
Tussilago farfara extracts are known to contain hepatotoxic and genotoxic pyrrolizidine alkaloids; animal studies show tumorigenicity and case reports link PA‑containing herbal use in pregnancy to infant liver damage, supporting a suspected reproductive/ developmental hazard (h=2). Evidence indicates a demonstrated toxic mechanism for PAs (genotoxic/hepatotoxic) rather than a purely theoretical structural alert (m=2). For topical cosmetic use, systemic exposure is expected to be low but measurable if PAs are present in the extract (e=1). (ECHA substance entry; PubMed carcinogenicity study; EFSA/PA reviews).
Alternativas seguras a tussilago farfara leaf extract en el embarazo | VeriMom
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Frequently asked questions
- ¿Es tussilago farfara leaf extract seguro durante el embarazo?
- Tussilago farfara extracts are known to contain hepatotoxic and genotoxic pyrrolizidine alkaloids; animal studies show tumorigenicity and case reports link PA‑containing herbal use in pregnancy to infant liver damage, supporting a suspected reproductive/ developmental hazard (h=2). Evidence indicates a demonstrated toxic mechanism for PAs (genotoxic/hepatotoxic) rather than a purely theoretical structural alert (m=2). For topical cosmetic use, systemic exposure is expected to be low but measurable if PAs are present in the extract (e=1). (ECHA substance entry; PubMed carcinogenicity study; EFSA/PA reviews).
- ¿Es tussilago farfara leaf extract seguro durante la lactancia?
- Same hazard drivers apply during lactation—PAs are hepatotoxic/genotoxic and have been implicated in neonatal/infant liver injury after maternal herbal use. Mechanistic data for PA toxicity apply (m=2). Topical use would generally give low but potentially measurable systemic exposure (e=1), so transfer in milk is plausible if maternal systemic levels occur. (ECHA; EFSA PA opinion; case reports and toxicology literature).
- ¿Es tussilago farfara leaf extract seguro para la piel del bebé?
- No infant‑specific studies found, so hazard and mechanism remain those from PA toxicity (h=2, m=2). Because infant skin has higher absorption (immature barrier, higher surface‑area:weight) and PAs are small molecule toxins that can be systemically available, exposure score is increased by +1 relative to adult topical use (adult e=1 → baby e=2). No data justify raising hazard or mechanism beyond adult scores. (EFSA/PA reviews; toxicology literature).
- ¿Cómo puntúa VeriMom a tussilago farfara leaf extract?
- VeriMom puntúa tussilago farfara leaf extract en 40/100 (riesgo medio) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a tussilago farfara leaf extract en el embarazo?
- Consulta nuestra lista de alternativas seguras a tussilago farfara leaf extract según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.