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¿Es phenolphthalein seguro durante el embarazo?

Reviewed by · Last reviewed

Ingredientes
phenolphthalein
RIESGO ALTO
20
/100
0

Alternativas seguras a phenolphthalein en el embarazo | VeriMom

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Sources & references

Authoritative references used to score this ingredient.

Frequently asked questions

¿Es phenolphthalein seguro durante el embarazo?
Phenolphthalein has harmonised CLP classifications for reproductive toxicity including H360 (per ECHA brief profile / Annex VI) and H361f (suspected of damaging fertility), which meets the criterion for H360-level evidence → h=3. There is experimental evidence of estrogenic activity/in vitro endocrine effects and genotoxicity in animal/in vitro studies supporting a demonstrated mechanism (m=2). For typical topical cosmetic use systemic absorption is likely low but measurable, so exposure is scored e=1. Sources: ECHA harmonised classification, NTP/animal carcinogenicity/genotoxicity literature, in vitro estrogenic reports.
¿Es phenolphthalein seguro durante la lactancia?
Harmonised classification includes reproductive concerns (H361f) and the substance has animal/genotoxic and in vitro estrogenic data; breastfeeding is scored h=2 because harmonised H361 (suspected reproductive hazard) supports 'suspected' rather than confirmed systemic teratogen for lactation exposure. Mechanistic data (in vitro estrogenic activity, genotoxicity) give m=2. Systemic absorption from topical use is likely low but measurable, so milk transfer risk is low but not negligible (e=1).
¿Es phenolphthalein seguro para la piel del bebé?
For infant topical exposure (0–3 yr) the hazard score is maintained at h=2 (suspected reproductive/toxic effects per harmonised H361; H360-level evidence applies to developmental systemic teratogenesis but infant-skin–specific teratogenic data are not available so h is not escalated to 3). No infant‑specific mechanistic data identified, so m=0 (do not increase m without infant-specific evidence). Adult topical absorption judged low but measurable (adult e=1), and per instruction baby skin exposure is increased by +1 → e=2. Overall infant dermal exposure could be higher due to immature barrier and higher surface-area-to-weight ratio. Sources cited below.
¿Cómo puntúa VeriMom a phenolphthalein?
VeriMom puntúa phenolphthalein en 20/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a phenolphthalein en el embarazo?
Consulta nuestra lista de alternativas seguras a phenolphthalein según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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