VeriMom¿Es n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine seguro durante el embarazo?
No harmonised CLP reproductive classifications (H360/H361) or SCCS/CIR safety assessment specific to CAS 10228-03-2 were identified. Regulatory sources show this specific compound (N,N'-dimethyl-N-hydroxyethyl-3‑nitro-p‑phenylenediamine; CAS 10228-03-2) is listed in EU/Member‑state cosmetic prohibitions for use in hair‑dye products, but that listing does not equal a harmonised reproductive hazard classification; peer‑reviewed reproductive or developmental studies on this exact substance were not found. Dermal absorption data are available for the p‑phenylenediamine class (measurable but low percent systemic absorption in human/in vitro studies), so for topical use a low but measurable exposure is assigned. Sources: EU cosmetics annex/regulatory listings and dermal absorption studies of p‑phenylenediamine. (See sources.)
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Frequently asked questions
- ¿Es n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine seguro durante el embarazo?
- No harmonised CLP reproductive classifications (H360/H361) or SCCS/CIR safety assessment specific to CAS 10228-03-2 were identified. Regulatory sources show this specific compound (N,N'-dimethyl-N-hydroxyethyl-3‑nitro-p‑phenylenediamine; CAS 10228-03-2) is listed in EU/Member‑state cosmetic prohibitions for use in hair‑dye products, but that listing does not equal a harmonised reproductive hazard classification; peer‑reviewed reproductive or developmental studies on this exact substance were not found. Dermal absorption data are available for the p‑phenylenediamine class (measurable but low percent systemic absorption in human/in vitro studies), so for topical use a low but measurable exposure is assigned. Sources: EU cosmetics annex/regulatory listings and dermal absorption studies of p‑phenylenediamine. (See sources.)
- ¿Es n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine seguro durante la lactancia?
- Same rationale as pregnancy: no specific reproductive/breastmilk transfer or lactation studies for this CAS were found, no harmonised reproductive classification. Dermal exposure from cosmetic use of PPD‑type hair dyes is measurable; therefore a low but measurable exposure during breastfeeding is assigned in the absence of direct data. Regulatory prohibitions limit expected use in cosmetics in jurisdictions listing the CAS.
- ¿Es n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine seguro para la piel del bebé?
- No infant‑specific toxicology or dermal transfer data were found for CAS 10228-03-2. Following the scoring rules, because the adult exposure is judged low but measurable (e=1) and infants/0–3‑year skin has higher permeability and surface‑area‑to‑weight, exposure is increased by +1 (e=2). There is no direct evidence to increase hazard (h) or mechanism (m) for infants.
- ¿Cómo puntúa VeriMom a n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine?
- VeriMom puntúa n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine en 93/100 (sin riesgos conocidos) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine en el embarazo?
- Consulta nuestra lista de alternativas seguras a n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.