VeriMom¿Es n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine seguro durante el embarazo?
SCCS concluded the substance is not safe for use as a hair‑dye because genotoxicity could not be ruled out; the ingredient is a secondary amine prone to nitrosation (theoretical formation of nitrosamines, which are reproductive/developmental toxicants in some cases), so I assign a structural/class‑based reproductive concern (h=1) and a theoretical mechanism via nitrosation (m=1). Topical use in hair dyes at up to ~1% on‑head gives low but measurable exposure (e=1). Source: SCCS opinion and submissions; note secondary‑amine / nitrosation statement.
Alternativas seguras a n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine en el embarazo | VeriMom
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- ¿Es n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine seguro durante el embarazo?
- SCCS concluded the substance is not safe for use as a hair‑dye because genotoxicity could not be ruled out; the ingredient is a secondary amine prone to nitrosation (theoretical formation of nitrosamines, which are reproductive/developmental toxicants in some cases), so I assign a structural/class‑based reproductive concern (h=1) and a theoretical mechanism via nitrosation (m=1). Topical use in hair dyes at up to ~1% on‑head gives low but measurable exposure (e=1). Source: SCCS opinion and submissions; note secondary‑amine / nitrosation statement.
- ¿Es n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine seguro durante la lactancia?
- Same rationale as for pregnancy: no direct reproductive/ lactation studies were found, but SCCS safety concerns (uncertainty about genotoxicity) and the compound’s propensity to nitrosate support a structural/theoretical concern (h=1, m=1). Dermal use leads to low but measurable exposure — breastfeeding exposure via maternal systemic absorption is therefore low but possible (e=1).
- ¿Es n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine seguro para la piel del bebé?
- No infant‑specific toxicology was located. Per instructions, because adult topical exposure is measurable (e=1) and infant skin has higher uptake, increase exposure score by +1 to e=2. Hazard and mechanism remain theoretical (h=1, m=1) in absence of direct developmental/infant data. SCCS restricted use for hair application; secondary‑amine nitrosation remains a contamination/indirect concern for infants.
- ¿Cómo puntúa VeriMom a n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine?
- VeriMom puntúa n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine en 67/100 (riesgo medio) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine en el embarazo?
- Consulta nuestra lista de alternativas seguras a n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.