¿Es hydroxyacetophenone seguro durante el embarazo?
CIR’s safety assessment (Cosmetic Ingredient Review, 2022 draft/final) concluded hydroxyacetophenone (p‑hydroxyacetophenone; CAS 99‑93‑4) is safe as used in cosmetics and found no reproductive/developmental hazard at use‑relevant exposures (NOAELs in animal studies reported but no reproductive signal at cosmetic exposures). No harmonised CLP reproductive classifications (H360/H361) were found on ECHA; company CLP notifications list general irritation/acute hazards but not reproductive classification. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
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Frequently asked questions
- ¿Es hydroxyacetophenone seguro durante el embarazo?
- CIR’s safety assessment (Cosmetic Ingredient Review, 2022 draft/final) concluded hydroxyacetophenone (p‑hydroxyacetophenone; CAS 99‑93‑4) is safe as used in cosmetics and found no reproductive/developmental hazard at use‑relevant exposures (NOAELs in animal studies reported but no reproductive signal at cosmetic exposures). No harmonised CLP reproductive classifications (H360/H361) were found on ECHA; company CLP notifications list general irritation/acute hazards but not reproductive classification. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
- ¿Es hydroxyacetophenone seguro durante la lactancia?
- There are no authoritative safety assessments (CIR/SCCS/harmonised CLP) indicating reproductive/lactation hazards or breast‑milk transfer for hydroxyacetophenone; available toxicology (CIR review, ECHA dossiers, and literature) does not identify specific lactation/breastfeeding risks at cosmetic use levels. No peer‑reviewed human lactation studies were identified. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
- ¿Es hydroxyacetophenone seguro para la piel del bebé?
- Hazard and mechanism remain not indicated by CIR/ECHA (h=0,m=0). Adult exposure was judged negligible for reproductive hazard in authoritative reviews; however, infant skin has a higher surface‑area:weight ratio and an immature barrier, so exposure scoring for baby skin is increased by +1 per your rules (adult e=0 → baby e=1) in absence of data proving zero dermal absorption. CIR found no reproductive concerns and performed dermal irritation/sensitization assessments but did not provide human dermal‑absorption data sufficient to demonstrate zero absorption. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
- ¿Cómo puntúa VeriMom a hydroxyacetophenone?
- VeriMom puntúa hydroxyacetophenone en 100/100 (sin riesgos conocidos) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a hydroxyacetophenone en el embarazo?
- Consulta nuestra lista de alternativas seguras a hydroxyacetophenone según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.