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¿Es hydrastis canadensis extract seguro durante el embarazo?

Animal developmental/reproductive studies of berberine (a major alkaloid in Hydrastis canadensis) show developmental/embryotoxic effects and maternal toxicity in rodent studies; berberine can cross the placenta (animal and in vitro data) and authoritative agencies advise avoiding goldenseal/berberine in pregnancy. No EU Annex II/III ban or harmonised CLP (H360/H361) was identified for the extract itself. Sources: PubMed developmental studies; ANSES/ESCOP guidance; PubMed review. (See sources.)

Ingredientes
hydrastis canadensis extract
RIESGO MEDIO
40
/100
0

Alternativas seguras a hydrastis canadensis extract en el embarazo | VeriMom

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Frequently asked questions

¿Es hydrastis canadensis extract seguro durante el embarazo?
Animal developmental/reproductive studies of berberine (a major alkaloid in Hydrastis canadensis) show developmental/embryotoxic effects and maternal toxicity in rodent studies; berberine can cross the placenta (animal and in vitro data) and authoritative agencies advise avoiding goldenseal/berberine in pregnancy. No EU Annex II/III ban or harmonised CLP (H360/H361) was identified for the extract itself. Sources: PubMed developmental studies; ANSES/ESCOP guidance; PubMed review. (See sources.)
¿Es hydrastis canadensis extract seguro durante la lactancia?
Berberine is reported to be excreted into breastmilk and agencies/authors advise against goldenseal/berberine during lactation because of potential infant exposure and risks (including bilirubin displacement/jaundice concerns). Evidence supports measurable transfer (mechanism demonstrated) although human quantitative milk data are limited.
¿Es hydrastis canadensis extract seguro para la piel del bebé?
No infant-specific reproductive toxicity data for topical cosmetic use were identified. The constituent berberine has demonstrated developmental hazards in animals, so a conservative hazard flag at class/constituent level is appropriate (h=1 for baby skin absent infant-specific data). Topical exposure on infant skin yields increased exposure score (+1) because infant skin barrier is immature and any measurable dermal absorption for adults becomes higher for infants; dermal absorption for plant alkaloids is low-to-moderate but not zero.
¿Cómo puntúa VeriMom a hydrastis canadensis extract?
VeriMom puntúa hydrastis canadensis extract en 40/100 (riesgo medio) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a hydrastis canadensis extract en el embarazo?
Consulta nuestra lista de alternativas seguras a hydrastis canadensis extract según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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