VeriMom¿Es fisetin seguro durante el embarazo?
No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).
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Frequently asked questions
- ¿Es fisetin seguro durante el embarazo?
- No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).
- ¿Es fisetin seguro durante la lactancia?
- No authoritative safety assessment (CIR or SCCS) or harmonised classification indicating harm to breastfed children was found. No controlled human data showing transfer into milk or adverse effects in suckling offspring; some animal pregnancy studies showed protective effects rather than toxicity. Dermal exposure from cosmetics would be expected to give low but measurable systemic exposure in adults, so a low exposure score is used. Self‑classified SDS statements claiming reproductive/breastfeeding hazard are present for some supplier documents but are not equivalent to harmonised CLH and were not used to increase the hazard score.
- ¿Es fisetin seguro para la piel del bebé?
- No infant‑specific hazard evidence was identified. Per the scoring rules, because fisetin shows measurable dermal absorption in principle (small flavonol) the exposure score for baby skin is increased by +1 relative to adults to account for immature barrier and higher surface‑area‑to‑weight; there is no direct data showing increased hazard or infant‑specific mechanism, so hazard and mechanism scores remain at default.
- ¿Cómo puntúa VeriMom a fisetin?
- VeriMom puntúa fisetin en 93/100 (sin riesgos conocidos) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a fisetin en el embarazo?
- Consulta nuestra lista de alternativas seguras a fisetin según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.