¿Es ethinylestradiol seguro durante el embarazo?
Ethinylestradiol (CAS 57-63-6) has a harmonised CLP classification as Repr. 1B (H360—may damage fertility or the unborn child) per ECHA, which meets the criterion for h=3. It is a potent synthetic estrogen with demonstrated estrogen receptor agonism and animal data showing adverse effects on fetal growth/survival, supporting m=2. For topical cosmetic use, systemic exposure from a cosmetic formulation would be negligible/very low, so e=0 (noting ethinylestradiol is primarily used as an oral/vaginal pharmaceutical rather than a cosmetic). ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.014.129?utm_source=openai))
Alternativas seguras a ethinylestradiol en el embarazo | VeriMom
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Frequently asked questions
- ¿Es ethinylestradiol seguro durante el embarazo?
- Ethinylestradiol (CAS 57-63-6) has a harmonised CLP classification as Repr. 1B (H360—may damage fertility or the unborn child) per ECHA, which meets the criterion for h=3. It is a potent synthetic estrogen with demonstrated estrogen receptor agonism and animal data showing adverse effects on fetal growth/survival, supporting m=2. For topical cosmetic use, systemic exposure from a cosmetic formulation would be negligible/very low, so e=0 (noting ethinylestradiol is primarily used as an oral/vaginal pharmaceutical rather than a cosmetic). ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.014.129?utm_source=openai))
- ¿Es ethinylestradiol seguro durante la lactancia?
- Harmonised classification H360 (Repr. 1B) equally flags lactation-related reproductive hazard (h=3). Mechanistically, ethinylestradiol is an estrogen receptor agonist with demonstrated endocrine activity (m=2). Human studies indicate transfer into breast milk is negligible with low‑dose combined hormonal contraceptives, so exposure via milk from typical systemic use is low but measurable (e=1); for topical cosmetic use systemic uptake would be expected to be very low. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.014.129?utm_source=openai))
- ¿Es ethinylestradiol seguro para la piel del bebé?
- Hazard (H360 Repr. 1B) remains (h=3). Mechanistic evidence of estrogenic activity supports m=2. For topical cosmetic use adult dermal exposure is expected to be negligible (adult e=0); per the scoring rules, baby skin exposure is increased by +1 (e=1) because infant skin is more permeable — although ethinylestradiol is not a typical cosmetic ingredient and meaningful topical cosmetic exposure is unlikely. Animal studies show prenatal/placental effects but no infant‑specific dermal data were found. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.014.129?utm_source=openai))
- ¿Cómo puntúa VeriMom a ethinylestradiol?
- VeriMom puntúa ethinylestradiol en 27/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a ethinylestradiol en el embarazo?
- Consulta nuestra lista de alternativas seguras a ethinylestradiol según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.