¿Es capryloyl salicylic acid seguro durante el embarazo?
Animal developmental data show effects at high doses (dermal application in pregnant rats: increased incomplete ossification at 100 mg/kg/day; NOAEL for developmental toxicity 40 mg/kg/day), so reproductive/developmental hazard is suspected based on animal evidence; there is no harmonised CLP reproductive classification and CIR concluded cosmetic use at reported concentrations is safe. Dermal absorption in vitro is low but measurable (~6% penetrated deeper than the stratum corneum in a 16 h Franz cell study), so exposure from typical topical cosmetic use is low but measurable.
Alternativas seguras a capryloyl salicylic acid en el embarazo | VeriMom
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Frequently asked questions
- ¿Es capryloyl salicylic acid seguro durante el embarazo?
- Animal developmental data show effects at high doses (dermal application in pregnant rats: increased incomplete ossification at 100 mg/kg/day; NOAEL for developmental toxicity 40 mg/kg/day), so reproductive/developmental hazard is suspected based on animal evidence; there is no harmonised CLP reproductive classification and CIR concluded cosmetic use at reported concentrations is safe. Dermal absorption in vitro is low but measurable (~6% penetrated deeper than the stratum corneum in a 16 h Franz cell study), so exposure from typical topical cosmetic use is low but measurable.
- ¿Es capryloyl salicylic acid seguro durante la lactancia?
- No direct data on excretion in milk were identified; because animal developmental effects exist (see pregnancy section) the ingredient is treated as a suspected reproductive/developmental hazard. Maternal topical exposure gives low but measurable dermal penetration (CIR data), so systemic exposure cannot be excluded though milk transfer data are absent.
- ¿Es capryloyl salicylic acid seguro para la piel del bebé?
- Do not increase hazard without infant-specific evidence; however exposure score is increased by +1 for infants because CIR reports measurable dermal penetration in adults (~6% beyond stratum corneum and ~17% in stratum corneum by tape‑strip), and infant skin has higher absorption per weight. There are no infant-specific safety studies; CIR considered cosmetic uses (max reported leave‑on 0.5%) acceptable given available data.
- ¿Cómo puntúa VeriMom a capryloyl salicylic acid?
- VeriMom puntúa capryloyl salicylic acid en 53/100 (riesgo medio) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a capryloyl salicylic acid en el embarazo?
- Consulta nuestra lista de alternativas seguras a capryloyl salicylic acid según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.