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HIGH RISK

¿Debo evitar tazarotene durante el embarazo? | VeriMom

Strong evidence of teratogenicity from animal studies and long-standing regulatory warnings (FDA labeling/former Category X). Tazarotene is a topical retinoid that is a prodrug for a retinoic acid receptor agonist (well‑characterized mechanism mediating developmental toxicity). Systemic absorption after topical use is low but measurable, so fetal exposure cannot be excluded. Sources: FDA prescribing information and peer‑reviewed reviews summarizing animal teratology and labeling. (See sources.)

ECHA regulatory hazard statements

  • H360D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

¿Es tazarotene seguro durante el embarazo?
Strong evidence of teratogenicity from animal studies and long-standing regulatory warnings (FDA labeling/former Category X). Tazarotene is a topical retinoid that is a prodrug for a retinoic acid receptor agonist (well‑characterized mechanism mediating developmental toxicity). Systemic absorption after topical use is low but measurable, so fetal exposure cannot be excluded. Sources: FDA prescribing information and peer‑reviewed reviews summarizing animal teratology and labeling. (See sources.)
¿Es tazarotene seguro durante la lactancia?
Animal data show transfer of radioactivity into milk after topical dosing and plausible transfer of drug‑related material via milk; mechanism (retinoid activity) is relevant and transfer documented in animals, so hazard is suspected. Systemic levels after topical use are low but measurable; human milk transfer data are limited. (See sources.)
¿Es tazarotene seguro para la piel del bebé?
Direct application to infant skin is not appropriate given retinoid pharmacology and developmental activity (mechanism: RAR agonism). If exposure is via contact with treated caregiver skin, infant exposure risk is higher than adult due to immature barrier and higher surface‑area‑to‑weight; animal data show milk transfer. No infant‑specific safety data support direct use. Exposure score increased +1 relative to adult because infant skin is more permissive. (See sources.)
¿Cómo puntúa VeriMom a tazarotene?
VeriMom puntúa tazarotene en 13/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a tazarotene en el embarazo?
Consulta nuestra lista de alternativas seguras a tazarotene según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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