¿Debo evitar salicylamide durante el embarazo? | VeriMom
ECHA REACH/registration data include Repr.2 / H361 notifications for salicylamide (CAS 65-45-2) submitted by registrants (not a harmonised Annex VI classification). This supports a 'suspected' reproductive hazard (h=2) but is not harmonised by the Commission. Mechanistic concern is class-based/theoretical (m=1) because salicylamide is a salicylate-related compound and salicylates are known to cross the placenta and be systemically available; direct mechanistic reproductive data for salicylamide are limited. Exposure from typical topical cosmetic use is expected to be low but measurable (evidence for dermal cosmetic exposure is limited), so e=1.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es salicylamide seguro durante el embarazo?
- ECHA REACH/registration data include Repr.2 / H361 notifications for salicylamide (CAS 65-45-2) submitted by registrants (not a harmonised Annex VI classification). This supports a 'suspected' reproductive hazard (h=2) but is not harmonised by the Commission. Mechanistic concern is class-based/theoretical (m=1) because salicylamide is a salicylate-related compound and salicylates are known to cross the placenta and be systemically available; direct mechanistic reproductive data for salicylamide are limited. Exposure from typical topical cosmetic use is expected to be low but measurable (evidence for dermal cosmetic exposure is limited), so e=1.
- ¿Es salicylamide seguro durante la lactancia?
- Registrants have notified H361 (Repr.2) for salicylamide; salicylate metabolites are known to be excreted in human milk (class-based evidence), so a suspected hazard to nursing infants is appropriate (h=2) but this is based on registrant classification and read-across from salicylates rather than a harmonised/regulatory SCCS/CIR conclusion for salicylamide specifically. Systemic exposure after topical use is likely low but non-zero (e=1).
- ¿Es salicylamide seguro para la piel del bebé?
- Hazard (h) and mechanism (m) are kept the same as adult because there is no infant-specific evidence to upscore hazard or mechanism. Exposure (e) is increased by +1 for infants (e=2) per your rules because infant skin has higher surface‑area‑to‑weight and an immature barrier and salicylamide is a small molecule with some dermal absorption potential; therefore infant dermal exposure is moderately greater than adult.
- ¿Cómo puntúa VeriMom a salicylamide?
- VeriMom puntúa salicylamide en 27/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a salicylamide en el embarazo?
- Consulta nuestra lista de alternativas seguras a salicylamide según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.