¿Debo evitar psoralea corylifolia fruit extract durante el embarazo? | VeriMom
Animal and in vitro studies report embryotoxicity and reproductive/developmental effects for Psoralea corylifolia extracts and its constituents (psoralens, bakuchiol), supporting a suspected reproductive hazard (h=2). Reviews and primary studies describe embryotoxicity and developmental toxicity in animal models and identify estrogenic activity for bakuchiol (mechanism demonstrated → m=2). Topical exposure is plausibly systemically available for psoralens and other small lipophilic constituents (percutaneous absorption and phototoxicity documented) so exposure from cosmetics is moderate (e=2). Sources: PMC review (systematic toxicology summary) and primary embryotoxicity/reproductive studies. (See sources list.)
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FAQ
- ¿Es psoralea corylifolia fruit extract seguro durante el embarazo?
- Animal and in vitro studies report embryotoxicity and reproductive/developmental effects for Psoralea corylifolia extracts and its constituents (psoralens, bakuchiol), supporting a suspected reproductive hazard (h=2). Reviews and primary studies describe embryotoxicity and developmental toxicity in animal models and identify estrogenic activity for bakuchiol (mechanism demonstrated → m=2). Topical exposure is plausibly systemically available for psoralens and other small lipophilic constituents (percutaneous absorption and phototoxicity documented) so exposure from cosmetics is moderate (e=2). Sources: PMC review (systematic toxicology summary) and primary embryotoxicity/reproductive studies. (See sources list.)
- ¿Es psoralea corylifolia fruit extract seguro durante la lactancia?
- Because systemic maternal exposure is plausible and animal data indicate reproductive/developmental toxicity, the ingredient is rated as suspected (h=2) for breastfeeding. Mechanistic data (psoralens, bakuchiol with demonstrated bioactivity including estrogenic effects) support m=2. Dermal/topical use can result in systemic absorption of psoralens/bakuchiol (documented in percutaneous studies), so exposure to nursing parent is moderate (e=2); no reliable data on milk transfer were identified.
- ¿Es psoralea corylifolia fruit extract seguro para la piel del bebé?
- Infant-specific evidence was not found, so hazard and mechanism scores match adult (h=2, m=2). Exposure score increased by +1 for baby skin (immature barrier and higher surface-area-to-weight) from adult e=2 to e=3; psoralens and other small constituents in extracts have measurable dermal absorption/phototoxicity, raising exposure concern for 0–3 yr skin.
- ¿Cómo puntúa VeriMom a psoralea corylifolia fruit extract?
- VeriMom puntúa psoralea corylifolia fruit extract en 33/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a psoralea corylifolia fruit extract en el embarazo?
- Consulta nuestra lista de alternativas seguras a psoralea corylifolia fruit extract según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.