VeriMom¿Debo evitar propylene glycol dicaprate durante el embarazo? | VeriMom
Authoritative CIR safety assessment of propylene glycol esters (which includes propylene glycol dicaprate/dicaprylate) reports no reproductive or developmental effects in a rat prenatal study (gavage to 1000 mg/kg/day) and concludes acceptable safety in cosmetics; no harmonised ECHA Annex VI classification (H360/H361) for this substance was found. Dermal/systemic exposure from cosmetic use is low but measurable (used in leave‑on products, and some PG diesters can enhance dermal penetration in vitro, though dicaprylate did not increase penetration of water‑soluble drugs in the CIR review). ([cir-safety.org](https://www.cir-safety.org/sites/default/files/PGEste_122014_FR.pdf))
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es propylene glycol dicaprate seguro durante el embarazo?
- Authoritative CIR safety assessment of propylene glycol esters (which includes propylene glycol dicaprate/dicaprylate) reports no reproductive or developmental effects in a rat prenatal study (gavage to 1000 mg/kg/day) and concludes acceptable safety in cosmetics; no harmonised ECHA Annex VI classification (H360/H361) for this substance was found. Dermal/systemic exposure from cosmetic use is low but measurable (used in leave‑on products, and some PG diesters can enhance dermal penetration in vitro, though dicaprylate did not increase penetration of water‑soluble drugs in the CIR review). ([cir-safety.org](https://www.cir-safety.org/sites/default/files/PGEste_122014_FR.pdf))
- ¿Es propylene glycol dicaprate seguro durante la lactancia?
- No data indicating reproductive toxicity, lactation-specific toxicity, or mechanisms for transfer to breast milk were identified in authoritative reviews. Given low systemic absorption from topical use reported in the CIR review, maternal systemic exposure (and therefore milk transfer) is expected to be low but measurable. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/PGEste_122014_FR.pdf))
- ¿Es propylene glycol dicaprate seguro para la piel del bebé?
- CIR documents reported uses of propylene glycol dicaprylate/dicaprate in baby lotions (reported use concentrations historically ~2.5%) and includes dermal data; no infant-specific reproductive or developmental harms were found. Because infant skin has higher surface‑area‑to‑weight and an immature barrier, exposure rating is increased by +1 versus adults (from low/measurable to moderate). No infant‑specific adverse data or mechanistic evidence were found. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/PGEste_122014_FR.pdf))
- ¿Cómo puntúa VeriMom a propylene glycol dicaprate?
- VeriMom puntúa propylene glycol dicaprate en 33/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a propylene glycol dicaprate en el embarazo?
- Consulta nuestra lista de alternativas seguras a propylene glycol dicaprate según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.