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¿Debo evitar n,n'-methylenebisacrylamide durante el embarazo? | VeriMom

There are peer‑reviewed developmental toxicity studies in mice reporting decreased fetal body weight and increased fetal variations with N,N'-methylenebisacrylamide (110-26-9), indicating suspected developmental hazard (NOAEL for developmental toxicity reported at 3 mg/kg/day; adverse effects at higher doses). No harmonised CLP (Annex VI) reproductive classification was identified. For typical topical cosmetic use, dermal exposure/absorption from finished products is expected to be negligible. (Toxicological Sciences 1998; ECHA substance information; product SDSs/MSDSs reporting reproductive hazard category in supplier documents).

ECHA regulatory hazard statements

  • H340

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

¿Es n,n'-methylenebisacrylamide seguro durante el embarazo?
There are peer‑reviewed developmental toxicity studies in mice reporting decreased fetal body weight and increased fetal variations with N,N'-methylenebisacrylamide (110-26-9), indicating suspected developmental hazard (NOAEL for developmental toxicity reported at 3 mg/kg/day; adverse effects at higher doses). No harmonised CLP (Annex VI) reproductive classification was identified. For typical topical cosmetic use, dermal exposure/absorption from finished products is expected to be negligible. (Toxicological Sciences 1998; ECHA substance information; product SDSs/MSDSs reporting reproductive hazard category in supplier documents).
¿Es n,n'-methylenebisacrylamide seguro durante la lactancia?
Same basis as pregnancy: animal developmental/reproductive studies show suspected developmental toxicity. There are no data showing transfer into human milk; for normal topical cosmetic use, exposure to a nursing infant via maternal milk is expected to be negligible. No authoritative cosmetic‑safety body (CIR/SCCS) reproductive clearance for this specific compound was located.
¿Es n,n'-methylenebisacrylamide seguro para la piel del bebé?
The hazard evidence (mouse developmental toxicity) supports a suspected reproductive/developmental hazard. Dermal exposure of infants (0–3 yr) is of greater concern than for adults because immature skin has higher surface‑area‑to‑weight and higher relative uptake; while adult topical cosmetic exposure is expected to be negligible, per the scoring rules infant exposure is increased by +1 when measurable absorption cannot be excluded. There are no infant‑specific toxicity data identified.
¿Cómo puntúa VeriMom a n,n'-methylenebisacrylamide?
VeriMom puntúa n,n'-methylenebisacrylamide en 39/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
¿Cuáles son las alternativas seguras a n,n'-methylenebisacrylamide en el embarazo?
Consulta nuestra lista de alternativas seguras a n,n'-methylenebisacrylamide según función similar y clasificación sin riesgos conocidos.

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Aviso Médico

Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.

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