VeriMom¿Debo evitar methylene di-t-butylcresol durante el embarazo? | VeriMom
ECHA lists 6,6'-di-tert‑butyl‑2,2'‑methylenedi‑p‑cresol (CAS 119‑47‑1) with a harmonised classification for reproductive toxicity (Repr. 1B, H360F — “May damage fertility”), which by the scoring rules yields h=3. Animal reproductive/developmental findings are reported in regulatory dossiers (developmental NOAEL/LOAEL in non‑rodents in EPA/registration material), but a specific molecular reproductive mechanism is not established in the literature (m=1). For routine topical cosmetic use dermal absorption is likely low but not zero (lipophilic high‑molecular phenolic antioxidant), so exposure for a pregnant adult is scored as low but measurable (e=1). Sources: ECHA harmonised classification and registration/assessment data and regulatory toxicology summaries.
ECHA regulatory hazard statements
- •H360F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- ¿Es methylene di-t-butylcresol seguro durante el embarazo?
- ECHA lists 6,6'-di-tert‑butyl‑2,2'‑methylenedi‑p‑cresol (CAS 119‑47‑1) with a harmonised classification for reproductive toxicity (Repr. 1B, H360F — “May damage fertility”), which by the scoring rules yields h=3. Animal reproductive/developmental findings are reported in regulatory dossiers (developmental NOAEL/LOAEL in non‑rodents in EPA/registration material), but a specific molecular reproductive mechanism is not established in the literature (m=1). For routine topical cosmetic use dermal absorption is likely low but not zero (lipophilic high‑molecular phenolic antioxidant), so exposure for a pregnant adult is scored as low but measurable (e=1). Sources: ECHA harmonised classification and registration/assessment data and regulatory toxicology summaries.
- ¿Es methylene di-t-butylcresol seguro durante la lactancia?
- Same harmonised reproductive classification (Repr. 1B, H360F) applies and supports a high hazard score (h=3). No clear mechanistic data specific to lactational transfer was found (m=1). For topical cosmetic use, maternal dermal exposure is expected to be low but measurable; breastmilk transfer is plausible for lipophilic compounds but was not documented in available studies, so exposure is scored as low (e=1). Regulatory guidance therefore flags this substance for reproductive concern.
- ¿Es methylene di-t-butylcresol seguro para la piel del bebé?
- Hazard remains high because of the harmonised Repr.1B/H360F classification (h=3). No infant‑specific mechanism data was identified (m=1). Because infant skin (0–3 yr) has higher absorption per body weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → baby e=2) where dermal absorption is measurable. No infant dermal studies were located to justify changing hazard or mechanism scores.
- ¿Cómo puntúa VeriMom a methylene di-t-butylcresol?
- VeriMom puntúa methylene di-t-butylcresol en 27/100 (riesgo alto) según el estado EU CosIng, clasificaciones ECHA y estudios PubMed.
- ¿Cuáles son las alternativas seguras a methylene di-t-butylcresol en el embarazo?
- Consulta nuestra lista de alternativas seguras a methylene di-t-butylcresol según función similar y clasificación sin riesgos conocidos.
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Aviso Médico
Esta información es solo para fines educativos y no constituye asesoramiento médico. Las puntuaciones de seguridad se basan en datos disponibles públicamente y pueden no reflejar todos los riesgos. Siempre consulte a su profesional de salud antes de usar cualquier producto durante el embarazo o la lactancia.